Results 11 to 20 of about 110,072 (307)
Xibei Gongye Daxue Xuebao, 2021 Low-frequency narrow-band noise is one of the important components in the slat noise. Based on the transient flow field analysis for multi-element airfoil 30P-30N, the main mode characteristics of the slat pressure fluctuation are analyzed by means of ...
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Biomarkers for Duchenne muscular dystrophy: myonecrosis, inflammation and oxidative stress
Disease Models & Mechanisms, 2020 Duchenne muscular dystrophy (DMD) is a lethal, X-linked disease that causes severe loss of muscle mass and function in young children. Promising therapies for DMD are being developed, but the long lead times required when using clinical outcome measures ...
Miranda D. Grounds +5 more
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Molecular Therapy: Methods & Clinical Development, 2020 Delivery of therapeutic transgenes with adeno-associated viral (AAV) vectors for treatment of myopathies has yielded encouraging results in animal models and early clinical studies.
Jennifer B. Kwon +7 more
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RNA Biology, 2023 Mutations in the DMD gene are causative for Duchenne muscular dystrophy (DMD). Antisense oligonucleotide (AON) mediated exon skipping to restore disrupted dystrophin reading frame is a therapeutic approach that allows production of a shorter but ...
Remko Goossens +4 more
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Functional rescue of dystrophin deficiency in mice caused by frameshift mutations using Campylobacter jejuni Cas9 [PDF]
, 2018 Duchenne muscular dystrophy (DMD) is a fatal, X-linked muscle wasting disease caused by mutations in the DMD gene. In 51% of DMD cases, a reading frame is disrupted because of deletion of several exons.
Cappellari, O +9 more
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Application of digital micromirror devices (DMD) in biomedical instruments
Journal of Innovative Optical Health Sciences, 2020 There is an ongoing technological revolution in the field of biomedical instruments. Consequently, high performance healthcare devices have led to remarkable economic developments in the medical hardware industry.
Ziyun Zhuang, Ho Pui Ho
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Increased levels of interleukin-6 exacerbate the dystrophic phenotype in mdx mice [PDF]
, 2015 Duchenne muscular dystrophy (DMD) is characterized by progressive lethal muscle degeneration and chronic inflammatory response. The mdx mouse strain has served as the animal model for human DMD. However, while DMD patients undergo extensive necrosis, the
Berardinelli, Maria Grazia +10 more
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Pharmacological inhibition of PKCθ counteracts muscle disease in a mouse model of duchenne muscular dystrophy [PDF]
, 2017 Inflammation plays a considerable role in the progression of Duchenne Muscular Dystrophy (DMD), a severe muscle disease caused by a mutation in the dystrophin gene. We previously showed that genetic ablation of Protein Kinase C θ (PKCθ) in mdx, the mouse
Benedetti, Anna +8 more
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Entropy, 2020 In the process of digital micromirror device (DMD) digital mask projection lithography, the lithography efficiency will be enhanced greatly by path planning of pattern transfer.
Yingzhi Wang +4 more
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