Results 1 to 10 of about 60,875 (277)

DMRT Transcription Factors in the Control of Nervous System Sexual Differentiation

open access: yesFrontiers in Neuroanatomy, 2022
Sexual phenotypic differences in the nervous system are one of the most prevalent features across the animal kingdom. The molecular mechanisms responsible for sexual dimorphism throughout metazoan nervous systems are extremely diverse, ranging from ...
Rafael Casado-Navarro   +1 more
doaj   +1 more source

Dystrophin gene editing by CRISPR/Cas9 system in human skeletal muscle cell line (HSkMC) [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2021
Objective(s): Duchene muscular dystrophy (DMD) is a progressive neuromuscular disease caused by mutations in the DMD gene, resulting in the absence of dystrophin expression leading to membrane fragility and myofibril necrosis in the muscle cells. Because
Mahintaj Dara   +5 more
doaj   +1 more source

Study on characteristics of flow structure and generation of narrow-band in low-frequency noise for a slat

open access: yesXibei Gongye Daxue Xuebao, 2021
Low-frequency narrow-band noise is one of the important components in the slat noise. Based on the transient flow field analysis for multi-element airfoil 30P-30N, the main mode characteristics of the slat pressure fluctuation are analyzed by means of ...

doaj   +1 more source

Patients’ perceptions on temporomandibular disorder treatment with hydrostatic oral splints - a pilot study

open access: yesBDJ Open, 2022
Objective To evaluate temporomandibular disorder (TMD) treatment with a prefabricated, hydrostatic oral splint (HOS) based on self-reported patient’s symptoms using a standardized questionnaire.
H. Sabbagh   +5 more
doaj   +1 more source

EXPLORING TRANSIENT, NEUTRONIC, REDUCED-ORDER MODELS USING DMD/POD-GALERKIN AND DATA-DRIVEN DMD [PDF]

open access: yesEPJ Web of Conferences, 2021
There is growing interest in the development of transient, multiphysics models for nuclear reactors and analysis of uncertainties in those models. Reduced-order models (ROMs) provide a computationally cheaper alternative to compute uncertainties. However,
Elzohery Rabab, Roberts Jeremy
doaj   +1 more source

Diagnostic Accuracy on Magnetic Resonance Imaging for the Diagnosis of Osteoarthritis of the Temporomandibular Joint [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2015
Objectives: Osteoarthritis, which is also called degenerative arthritis or degenerative joint disease, is primarily a disease that results from the breakdown and loss of cartilage in joints. The purpose of this study was to investigate the diagnostic
Shinya Yura   +2 more
doaj   +1 more source

DMD antisense oligonucleotide mediated exon skipping efficiency correlates with flanking intron retention time and target position within the exon

open access: yesRNA Biology, 2023
Mutations in the DMD gene are causative for Duchenne muscular dystrophy (DMD). Antisense oligonucleotide (AON) mediated exon skipping to restore disrupted dystrophin reading frame is a therapeutic approach that allows production of a shorter but ...
Remko Goossens   +4 more
doaj   +1 more source

A novel mouse model of Duchenne muscular dystrophy carrying a multi-exonic Dmd deletion exhibits progressive muscular dystrophy and early-onset cardiomyopathy

open access: yesDisease Models & Mechanisms, 2020
Duchenne muscular dystrophy (DMD) is a life-threatening neuromuscular disease caused by the lack of dystrophin, resulting in progressive muscle wasting and locomotor dysfunctions.
Tatianna Wai Ying Wong   +13 more
doaj   +1 more source

Dynamic mode decomposition of numerical data in natural circulation

open access: yesBrazilian Journal of Radiation Sciences, 2021
Dynamic mode decomposition (DMD) has been used for experimental and numerical data analysis in fluid dynamics. Despite of its advantages, the application of the DMD methodology to investigate the natural circulation in nuclear reactors are very scarce in
José Luiz Horacio Faccini
doaj   +1 more source

Home - About - Disclaimer - Privacy