Results 41 to 50 of about 3,938 (202)

Corneal Allograft Rejection: Immunopathogenesis to Therapeutics [PDF]

open access: yes, 2014
Corneal transplantation is among the most successful solid organ transplants. However, despite low rejection rates of grafts in the ‘low-risk’ setting, rejection can be as high as 70% when grafted into ‘high-risk’ recipient beds. Under normal homeostatic
Hamrah, Pedram, Qazi, Yureeda
core   +1 more source

Photorefractive keratectomy after DMEK for corneal decompensation by phakic IOL [PDF]

open access: yes, 2022
Purpose: To provide the first description of photorefractive keratectomy (PRK) for the correction of mild residual refractive error after Descemet membrane endothelial keratoplasty (DMEK). Methods: A case report.
Amich, Nicolas   +5 more
core   +2 more sources

Femtosecond laser and microkeratome-assisted Descemet stripping endothelial keratoplasty: first clinical results [PDF]

open access: yes, 2013
Purpose: To evaluate the use of a femtosecond laser combined with a microkeratome in the preparation of posterior corneal disks for Descemet stripping automated endothelial keratoplasty (DSAEK).
Costa, E   +5 more
core   +1 more source

Graft rejection episodes after keratoplasty in Japanese eyes

open access: yesScientific Reports, 2023
We aimed to investigate the clinical characteristics and risk factors for graft rejection after keratoplasty in Japanese patients. We enrolled 730 cases (566 patients) of penetrating keratoplasty (PK, N = 198), Descemet’s stripping automated endothelial ...
Haguku Wajima   +7 more
doaj   +1 more source

Preclinical testing of small diameter Descemet membrane endothelial keratoplasty grafts to increase tissue availability.

open access: yesPLoS ONE, 2021
In this study, we describe a process of preparing, surgically manipulating, and validating a novel "small diameter" 4mm circular Descemet membrane endothelial keratoplasty (DMEK) graft in vitro.
Sorcha Ní Dhubhghaill   +5 more
doaj   +1 more source

Diagnosis and management of iridocorneal endothelial syndrome [PDF]

open access: yes, 2015
The iridocorneal endothelial (ICE) syndrome is a rare ocular disorder that includes a group of conditions characterized by structural and proliferative abnormalities of the corneal endothelium, the anterior chamber angle, and the iris.
Ambrosio, Oriella   +5 more
core   +2 more sources

Sustained activation of the unfolded protein response induces cell death in Fuchs' endothelial corneal dystrophy [PDF]

open access: yes, 2017
Purpose: The unfolded protein response (UPR) is believed to play a role in the pathogenesis of Fuchs' endothelial corneal dystrophy (FECD). The purpose of this study was to investigate whether unfolded proteins accumulate in the corneal endothelium in ...
Hashimoto, Keisuke   +12 more
core   +1 more source

Generation of a Novel Col8a2P2A‐CreERT2 Mouse Line Enables Targeted Genetic Manipulation of Corneal Endothelial Cells and Modeling of Endothelial Decompensation

open access: yesgenesis, Volume 64, Issue 2, April 2026.
ABSTRACT The corneal endothelium is a monolayer of specialized cells that maintains stromal deturgescence and transparency, functions essential for vision. Despite its clinical importance, the developmental origins and homeostatic programs of the endothelium remain poorly understood, in part due to the lack of a lineage‐specific genetic driver.
Yong Yuan   +9 more
wiley   +1 more source

Clinical and material degradations of intraocular lenses: A review [PDF]

open access: yes, 2019
Purpose: To review the published scientific literature concerning clinical and material degradations of intraocular lenses after implantation in cataract surgery.
Hull, C.   +2 more
core   +1 more source

Clinical outcomes of the PAUL glaucoma implant in primary open‐angle and pseudoexfoliative glaucoma eyes after failed glaucoma surgeries

open access: yesActa Ophthalmologica, Volume 104, Issue 2, Page e183-e190, March 2026.
Abstract Purpose This study assesses the PAUL® glaucoma implant (PGI) in primary open angle glaucoma (POAG) and pseudoexfoliative glaucoma (PEXG) after failed glaucoma surgery. Given PEXG's more aggressive nature, limited research exists on PGI outcomes in this subgroup. This study aims to compare PGI's efficacy and safety in both conditions. Methods A
Constance Liegl   +8 more
wiley   +1 more source

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