Transient peripheral edema following displaced corneal graft after descemet stripping automated endothelial keratoplasty (DSAEK): case presentation [PDF]
BMC Ophthalmology, 2011 Background Descemet's Stripping with Automated Endothelial Keratoplasty (DSAEK) is constantly gaining popularity in the management of endothelial dysfunctions such as bullous keratopathy or Fuchs' dystrophy.
Kymionis George D +3 more
doaj +3 more sources
Fuchs Endothelial Corneal Dystrophy [PDF]
The Ocular Surface, 2010 Fuchs endothelial corneal dystrophy (FECD) is characterized by progressive loss of corneal endothelial cells, thickening of Descement's membrane and deposition of extracellular matrix in the form of guttae. When the number of endothelial cells becomes critically low, the cornea swells and causes loss of vision. The clinical course of FECD usually spans
Hussain, Elhalis +2 more
exaly +5 more sources
Fuchs endothelial corneal dystrophy: current perspectives
Clinical Ophthalmology, 2016 Gustavo Vedana, Guadalupe Villarreal Jr, Albert S Jun Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, MD, USA Abstract: Fuchs endothelial corneal dystrophy (FECD) is the most common corneal dystrophy and frequently results in ...
Vedana G, Villarreal Jr G, Jun AS
doaj +4 more sources
Rare Association of Bilateral Central Salzmann Nodular Degeneration and Fuchs Endothelial Dystrophy Managed by DMEK: A Case Report [PDF]
LifeSalzmann nodular degeneration is a slowly progressive, rare, degenerative disease of the cornea, usually associated with other ocular pathologies such as dry eye disease, previous ocular surgery, involving the peripheral cornea.
Alina Gabriela Gheorghe +5 more
doaj +2 more sources
Regenerative medicine in Fuchs' endothelial corneal dystrophy
Taiwan Journal of Ophthalmology, 2021 The management of Fuchs' endothelial corneal dystrophy (FECD) has evolved rapidly since the introduction of endothelial keratoplasty (EK). In recent years, advances in our understanding of endothelial cell biology, in particular with respect to the ...
Amy E Yuan, Roberto Pineda
doaj +3 more sources
Generation of a Novel Col8a2<sup>P2A-CreERT2</sup> Mouse Line Enables Targeted Genetic Manipulation of Corneal Endothelial Cells and Modeling of Endothelial Decompensation. [PDF]
GenesisABSTRACT The corneal endothelium is a monolayer of specialized cells that maintains stromal deturgescence and transparency, functions essential for vision. Despite its clinical importance, the developmental origins and homeostatic programs of the endothelium remain poorly understood, in part due to the lack of a lineage‐specific genetic driver.
Yuan Y +9 more
europepmc +2 more sources
Exploring the histopathological signature of repeat-mediated Fuchs endothelial corneal dystrophy. [PDF]
Acta OphthalmolAbstract Purpose To determine the histological differences between Fuchs endothelial corneal dystrophy (FECD) cases with and without the most common genetic risk factor, expansion of a CTG repeat (CTG18.1) within the TCF4 gene. Methods Formalin‐fixed paraffin‐embedded corneal tissues were compared retrospectively, and CTG18.1 status was determined from
Kladny AS +5 more
europepmc +2 more sources
Mini descemet membrane stripping (m-DMES) in patients with Fuchs' endothelial dystrophy: A new method. [PDF]
Saudi J Ophthalmol, 2017 We present two cases with focal corneal edema due to Fuchs' endothelial dystrophy that were successfully treated with mini Descemet membrane stripping (m-DMES) (diameter of 3-4 mm; at the area of preexisting focal corneal edema) without endothelial ...
Kymionis GD +6 more
europepmc +4 more sources
Distribution and Surgical Treatment of Corneal Dystrophies Over Eight Decades (1945–2024): An Analysis of Histopathologically Confirmed Cases from a German Center [PDF]
Journal of Epidemiology and Global HealthBackground Corneal dystrophies are inherited disorders that can lead to significant visual impairment and often require surgical intervention in advanced stages.
Othmane Touirssa +6 more
doaj +2 more sources
Changing trends in penetrating keratoplasty indications at a tertiary eye care center in Budapest, Hungary between 2006 and 2017 [PDF]
International Journal of Ophthalmology, 2020 AIM: To analyze the changing trends in penetrating keratoplasty (PKP) indications. METHODS: This retrospective study included all patients with PKP between 2006 and 2017. Patients were classified using histological diagnoses.
Milán Tamás Pluzsik +7 more
doaj +1 more source