Results 11 to 20 of about 8,757 (220)
Fuchs endothelial corneal dystrophy: The vicious cycle of Fuchs pathogenesis
Progress in Retinal and Eye Research, 2021 Fuchs endothelial corneal dystrophy (FECD) is the most common primary corneal endothelial dystrophy and the leading indication for corneal transplantation worldwide. FECD is characterized by the progressive decline of corneal endothelial cells (CECs) and the formation of extracellular matrix (ECM) excrescences in Descemet's membrane (DM), called guttae,
Stephan Ong Tone +5 more
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Genetic mutations and molecular mechanisms of Fuchs endothelial corneal dystrophy
Eye and Vision, 2021 Background Fuchs endothelial corneal dystrophy is a hereditary disease and the most frequent cause of corneal transplantation in the worldwide. Its main clinical signs are an accelerated decrease in the number of endothelial cells, thickening of Descemet’
Xuerui Liu +6 more
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Long-Term Results after DMEK (Descemet’s Membrane Endothelial Keratoplasty) [PDF]
, 2020 Ziel der Arbeit: Evaluation der langfristigen Ergebnisse sowie der Komplikationsrate nach Descemet’s Membran Endothelialen Keratoplastik (DMEK) Methoden: Eine cross-sectional, Fall-Serien Studie.
Wardeh, Rima
core +1 more source
Frontiers in Medicine, 2021 Background: Our study aimed to determine the correlation between the clinical staging of Fuchs' endothelial corneal dystrophy (FECD), rate of endothelial cell loss, and corneal biomechanical properties.Methods: This study combined a longitudinal ...
Usanee Reinprayoon +4 more
doaj +1 more source
Application of convolutional neural networks to define Fuchs endothelial dystrophy
Офтальмохирургия, 2022 Purpose. To evaluate the application of convolutional neural networks for the automatic detection of Fuchs’ dystrophy. Material and methods. The study included 700 biomicroscopic images of the corneal endothelium (Tomey EM-3000) randomly selected from ...
S.V. Shukhaev +3 more
doaj +1 more source
Increased Corneal Endothelial Cell Migration in Fuchs Endothelial Corneal Dystrophy
Ophthalmology Science, 2021 Purpose: To investigate if corneal endothelial cells (CECs) in Fuchs endothelial corneal dystrophy (FECD) have altered cellular migration compared with normal controls. Design: Comparative analysis.
Stephan Ong Tone, MDCM, PhD +5 more
doaj +1 more source
Evolving Therapies for Fuchs Endothelial Dystrophy [PDF]
European Ophthalmic Review, 2018 Fuchs endothelial corneal dystrophy (FED) is one of the leading indications for corneal transplantation. Over the last two decades we have seen a significant shift in transplantation procedures for endothelial disease away from penetrating keratoplasty to small incision procedures such as Descemet stripping automated endothelial keratoplasty and ...
Yu Qiang, Soh +2 more
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Fuchs Endothelial Corneal Dystrophy [PDF]
JAMA Ophthalmology, 2014 First described more than a century ago, Fuchs endothelial corneal dystrophy (FECD) is a common disease characterized by progressive loss of endothelial cells, thickening of the Descemet membrane, and deposition of extracellular matrix in the form of guttae.
Angela Y, Zhu +2 more
openaire +2 more sources
Peroxiredoxin-1 regulates lipid peroxidation in corneal endothelial cells
Redox Biology, 2020 Corneal transparency is maintained by a monolayer of corneal endothelial cells. Defects in corneal endothelial cells (CEnCs) can be rectified surgically through transplantation.
Matthew Lovatt +5 more
doaj +1 more source