Results 51 to 60 of about 23,731 (232)

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

Effectiveness of data auditing as a tool to reinforce good research data management (RDM) practice: a Singapore study

BMC Medical Ethics, 2021
Background Institutions, funding agencies and publishers are placing increasing emphasis on good research data management (RDM). RDM lapses in medical science can result in questionable data and cause the public’s confidence in the scientific community ...
Hui Xing Lau, Ser Lin Celine Lee, Yusuf Ali   +2 more
doaj   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Beyond Transconductance: Cell‐Polymer Coupling Determines Fidelity in Action Potential Recording via Electrolyte‐Gated Polymer Transistors

Advanced Science, EarlyView.
High electrical performance alone does not guarantee efficient bioelectronic signal transduction. Despite excellent mixed ionic‐electronic conduction, recordings from cardiomyocytes reveal that p(g2T‐TT)‐based OECTs predominantly transduce field potential FP‐like signals due to weak cell‐polymer coupling.
Giulia Zoe Zemignani, Elena Mancinelli, Gabriele Tullii, Aleksandr Khudiakov, Cristiano Bortolotti, Shubham Tanwar, Peter J. Schwartz, Luca Sala, Maria Rosa Antognazza, Mario Caironi, Adrica Kyndiah   +10 more
wiley   +1 more source

Alles anders - alles gleich: Ein Überblick über Datenmanagementplanung und DMP-Tools

, 2022
Vortrag vom 23.06.2022 bei den Thüringer FDM-Tagen 2022 Talk on 23/06/2022 at Thuringian RDM-Days 2022 ...
openaire   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Thermoresponsive Colloidal Molecules

, 2010
We fabricated thermoresponsive colloidal molecules of ca. 250 nm size. Electron- and scanning force microscopy reveal the dumbbell-shaped morphology. The temperature dependence of the size and aspect ratio (ca.
Ballauff, Matthias, Drechsler, Markus, Hanske, Christoph, Harnau, Ludger, Hoffmann, Martin, Hund, Markus, Lu, Yan, Siebenbuerger, Miriam, Wagner, Claudia S.   +8 more
core   +1 more source

In Situ Polymerized Composite Electrolytes for High‐Performance Solid‐State Lithium Batteries: A Review

Advanced Science, EarlyView.
This review systematically explores the recent advances in in situ polymerized composite polymer electrolytes (CPEs) for solid‐state lithium batteries. It covers the fundamentals of reaction mechanisms, monomer chemistry, and their impact on interfacial stability, ionic conductivity, and electrochemical performance.
Jialin Li, Yufen Yan, Xiaoju Wang, Yuhui Huang, Zhen Huang, Lingjie Zhang, Ningzhong Bao, Zijian Hong, Yongjun Wu, Dali Ji   +9 more
wiley   +1 more source

Ankle phenomenon in the cosmic ray energy spectrum

, 2012
The author has suggested that the knee phenomenon in the cosmic ray energy spectrum at 3 PeV can be explained as a split between a radiation-dominated expansion and a matter-dominated expansion of an expanding heat bath.
Tomozawa, Yukio
core   +1 more source

Vergleich der DMP-Tools RDMO, DMPRoadmap und Data Steward Wizard

, 2019
Ein Ziel des Arbeitspakets „Datenmanagementpläne“ ist es, Empfehlungen für bestehende DMP-Tools abzugeben, die die Forschenden hinsichtlich der neuen Anforderungen der FördergeberInnen unterstützen.
Haselwanter, Thomas, Miksa, Tomasz, Thöricht, Heike   +2 more
openaire   +2 more sources