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The Antigenicity of Bacterial DNA
2002DNA is a complex macromolecule whose immunological properties vary with base sequence and backbone structure. Although now recognized as important for normal immunity, the antigenic and immunogenic properties of DNA were originally conceptualized entirely in the context of systemic lupus erythematosus (SLE).
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Use of DNA reassociation in bacterial classification
Canadian Journal of Microbiology, 1988The reassociation properties of DNA provide invaluable taxonomic tools. Different methods may give different reassociation values. However, the thermal stability of reassociated DNA strands (a measurement that seems independent of method) is useful in delineating genomic species.
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DNA Supercoiling Catalyzed by Bacterial Gyrase
DNA gyrase is an essential type II topoisomerase that is conserved across bacteria species and has an essential function of resolving overwound (positive supercoiled) DNA and introducing negative supercoils into relaxed DNA. The overall catalytic activity of gyrase can be determined using in vitro assays utilizing purified enzyme subunits and a DNA ...Samika, Joshi, Neil, Osheroff
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Hybridization of Bacterial DNA on Filters
Cold Spring Harbor Protocols, 2006Joseph, Sambrook, David W, Russell
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DNA vaccines and bacterial DNA in immunity
2002This thesis describes DNA-based vaccination and the importance of bacterial DNA in different immunological perspectives. Intranasal (i.n.) DNA vaccination utilizing a plasmid encoding the chlamydial heat shock protein 60 (p-hsp-60) generated lower bacterial burden and reduced pathology in the lungs of mice after subsequent infection with C. pneumoniae.
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Bacterial DNA supercoiling and
Journal of Molecular Biology, 1991Li-Shan Hsieh +2 more
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