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Immobilization of plasmid DNA in bacterial ghosts
Journal of Controlled Release, 2005The development of novel delivery vehicles is crucial for the improvement of DNA vaccine efficiency. In this report, we describe a new platform technology, which is based on the immobilization of plasmid DNA in the cytoplasmic membrane of a bacterial carrier.
W. Haidinger+5 more
openaire +4 more sources
Mechanisms of immune stimulation by bacterial DNA [PDF]
Bacterial DNA promotes powerful immune system activation because of its content of characteristic sequence motifs. These sequences induce cellular changes that promote inflammation and the generation of Thl responses. This activation involves internalization of DNA as well as the activation of NF-κB and stress kinases.
openaire +2 more sources
A Toll-like receptor recognizes bacterial DNA
Nature, 2000H. Hemmi+10 more
semanticscholar +1 more source
DNA targeting and interference by a bacterial Argonaute nuclease
Nature, 2020A. Kuzmenko+11 more
semanticscholar +1 more source
Composition and functions of bacterial membrane vesicles
Nature Reviews Microbiology, 2023M. Toyofuku+3 more
semanticscholar +1 more source
CpG motifs in bacterial DNA trigger direct B-cell activation
Nature, 1995A. Krieg+7 more
semanticscholar +1 more source
DNA bacterial load in children with bacteremic pneumococcal community-acquired pneumonia
European Journal of Clinical Microbiology and Infectious Diseases, 2013S. Esposito+9 more
semanticscholar +1 more source
DNA bacterial load in children and adolescents with pneumococcal pneumonia and empyema
European Journal of Clinical Microbiology and Infectious Diseases, 2011C. Muñoz-Almagro+5 more
semanticscholar +1 more source