Results 161 to 170 of about 2,877,234 (303)

Machine learning-powered single-molecule cancer diagnosis using DNA origami tags. [PDF]

Sci Adv
Xiong J, He Z, Guan W, Zhi S, Sun X, Yang Z, Ma J, Fan C, Wang L, Chao J.   +9 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Compartment-specific eccDNA patterns reveal senescence associated biomarkers in hUC-MSCs. [PDF]

Sci Rep
Yan Q, Xu Q, Yu Y, Wang D, Zhong W, Wu Y, Liu C, Xu Z, Fan D.   +8 more
europepmc   +1 more source

Hexamminecobalt(III)-induced condensation of calf thymus DNA: circular dichroism and hydration measurements

Nucleic Acids Res., 2001
B. Kankia, V. Buckin, V. Bloomfield
semanticscholar   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Programmable no-nonspecific genetic analytical system via dual-circle-based rolling circle amplification with an efficient CRISPR/Cas12a biosensing strategy. [PDF]

Sci Rep
Feng C, Wang Y, Liu C, Dong F, Guo M, Liu F, Li Y, Zhang L.   +7 more
europepmc   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Simple in vitro single-stranded linear and circular DNA preparation, functional selection, and validation using phosphor-derived modifications. [PDF]

J Biol Chem
Hamidi SV, Aguilar-Sánchez V, Héroux VL, Perreault J.   +3 more
europepmc   +1 more source

Defective herpes simplex virus DNA: circular and circular-linear molecules resembling rolling circles.

Journal of General Virology, 1978
Y. Becker, Y. Asher, E. Weinberg-Zahlering, S. Rabkin, A. Friedmann, E. Kessler   +5 more
semanticscholar   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source