Results 251 to 260 of about 3,017,680 (323)

Chemical circularization of in vitro transcribed RNA for exploring circular mRNA design. [PDF]

Nat Commun
Wasinska-Kalwa M, Mamot A, Czubak K, Frankowska K, Rajkiewicz AA, Spiewla T, Warminski M, Pilch Z, Szulc-Gasiorowska M, Siekan K, Dziembowski A, Nowis D, Golab J, Kowalska J, Jemielity J.   +14 more
europepmc   +1 more source

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

Advanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang, Ahmed Refaat, Haoqin Li, Douer Zhu, Ziqiu Tong, Joseph Anthony Nicolazzo, Bo Peng, Hua Bai, Lars Esser, Nicolas Hans Voelcker   +9 more
wiley   +1 more source

Complete genome sequence of strain M4-SHS-6, a potential new member of the genus <i>Acidithiobacillus</i>. [PDF]

Microbiol Resour Announc
Zhou M, Yu T, Lan X, Zhu S, Chen J.
europepmc   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Characterization of Extrachromosomal Circular DNA in Primary and Cisplatin-Resistant High-Grade Serous Ovarian Cancer. [PDF]

Genes (Basel)
Wang Y, Li H, Li Q, Li Y, Wu H, Ge Y, Zhu X, Zheng Z, Sun Z.   +8 more
europepmc   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Complete genome sequence of <i>Xanthomonas euvesicatoria</i> pv. <i>polysciadis</i> pathotype strain Pgu1^PT, a phytopathogenic bacterium isolated from <i>Polyscias guilfoylei</i> (geranium aralia). [PDF]

Microbiol Resour Announc
Wu C-F, Lee S, Huang Y-C, Chu C-C.
europepmc   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Development of circular AAV cargos for targeted seamless insertion with large serine integrases. [PDF]

Mol Ther Methods Clin Dev
Estes BJG, Gandhi N, Von Stetina JR, Paudel D, Nan AX, Amin P, Rose J, Wu S, Zheng K, Zhang Y, Cochrane JC, Finn JD, Xie J.   +12 more
europepmc   +1 more source

From Low Symmetry to High Dissymmetry: Chiral Plasmonic Films of Binary and Nanobipyramid Assemblies

Advanced Functional Materials, EarlyView.
This work develops highly dissymmetric chiral plasmonic thin films by helically assembling gold nano bipyramids within a liquid‐crystal template. Engineering of the chiroptical response is achieved by varying particle size and geometry, as well as preparing binary assemblies.
Martyna Wasiluk, Claire Goldmann, Maciej Bagiński, Mateusz Pawlak, PawełW. Majewski, Julia Abramowicz, Piotr Roszkowski, Lukas Rebholz, Carsten Rockstuhl, Cyrille Hamon, Wiktor Lewandowski   +10 more
wiley   +1 more source