Results 41 to 50 of about 2,877,234 (303)
Nature Communications, 2019 Smacoviridae is a family of small (~2.5 Kb) CRESS-DNA (Circular Rep Encoding Single-Stranded (ss) DNA) viruses. These viruses have been found in faeces, were thought to infect eukaryotes and are suspected to cause gastrointestinal disease in humans ...
C. Díez-Villaseñor +1 more
semanticscholar +1 more source
BMC Bioinformatics, 2019 Background Circular DNA has recently been identified across different species including human normal and cancerous tissue, but short-read mappers are unable to align many of the reads crossing circle junctions hence limiting their detection from short ...
Iñigo Prada-Luengo +3 more
doaj +1 more source
Circular Dichroism of Chiral Molecules in DNA-Assembled Plasmonic Hotspots. [PDF]
ACS Nano, 2018 The chiral state of a molecule plays a crucial role in molecular recognition and biochemical reactions. Because of this and owing to the fact that most modern drugs are chiral, the sensitive and reliable detection of the chirality of molecules is of ...
L. Kneer +5 more
semanticscholar +1 more source
The Knot Spectrum of Confined Random Equilateral Polygons
Computational and Mathematical Biophysics, 2014 It is well known that genomic materials (long DNA chains) of living organisms are often packed compactly under extreme confining conditions using macromolecular self-assembly processes but the general DNA packing mechanism remains an unsolved problem. It
Diao Y. +4 more
doaj +1 more source
Журнал микробиологии, эпидемиологии и иммунобиологии, 2016 Aim. Evaluate significance of covalently closed circular DNA of hepatitis В virus as a marker for detection of occult viral hepatitis В in Uzbekistan population with hepatitis of various genesis. Materials and methods.
A. V. Semenov +6 more
doaj +1 more source
Screening for inhibitor of episomal DNA identified dicumarol as a hepatitis B virus inhibitor.
PLoS ONE, 2019 Currently, there is no available therapy to eradicate hepatitis B virus (HBV) in chronically infected individuals. This is due to the difficulty in eliminating viral covalently closed circular (ccc) DNA, which is central to the gene expression and ...
Fumihiko Takeuchi +16 more
doaj +1 more source
Circular DNA elements of chromosomal origin are common in healthy human somatic tissue
Nature Communications, 2018 The human genome is generally organized into stable chromosomes, and only tumor cells are known to accumulate kilobase (kb)-sized extrachromosomal circular DNA elements (eccDNAs).
Henrik D. Møller +11 more
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell +14 more
wiley +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Animals, 2023 Circular replicase-encoding single-stranded (CRESS) DNA viruses and other circular DNA agents are increasingly found in various samples and animals. A specific class of these agents—termed bovine meat and milk factors (BMMF)—has been supposed to act as a
Marie-Thérèse König +7 more
doaj +1 more source