Results 51 to 60 of about 2,244,972 (310)

Circular on Development of the Medium-Term Revenue Strategy (MTRS) for FY 2023/2024-2026-2027

open access: yes, 2022
The purpose of this Circular is to inform the Government Ministries, Departments and Agencies (MDAs) and the County Governments of the Government's intention to develop a Strategy to enhance revenue mobilization to facilitate implementation of Government

core  

Circular on Schedule of Submission of the 2023 Every Two-Year Declaration of Income. Assets and Liabilities Forms [PDF]

open access: yes, 2023
Reference is made to Circular Ref. No.PSC/218/110/XII VOL.Vll/(19) dated 18th October, 2023 providing guidelines for receiving and processing of the 2023 every two year declarations of income assets and liabilities forms by organizations. In this regard,
The Public Service Commission
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First Insights into the Occurrence of Circular Single-Stranded DNA Genomes in Asian and African Cattle

open access: yesAnimals, 2023
Circular replicase-encoding single-stranded (CRESS) DNA viruses and other circular DNA agents are increasingly found in various samples and animals. A specific class of these agents—termed bovine meat and milk factors (BMMF)—has been supposed to act as a
Marie-Thérèse König   +7 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Genomic insertion of lentiviral DNA circles directed by the yeast Flp recombinase

open access: yesBMC Biotechnology, 2008
Background Circular forms of viral genomic DNA are generated during infection of cells with retroviruses like HIV-1. Such circles are unable to replicate and are eventually lost as a result of cell division, lending support to the prevalent notion that ...
Yáñez-Muñoz Rafael J   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Clivagem e interação de um novo complexo de Ferro (II) com DNA plasmidial e proteínas [PDF]

open access: yes, 2010
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Curso de Química.A interação entre compostos metálicos e biomoléculas tem sido alvo de importantes estudos na atualidade, devido a sua importância em ...
Bussi, Giselle Giovana Azzolini
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Circular DNA in Isolated Chromoplasts

open access: yesZeitschrift für Naturforschung C, 1974
Abstract Flower chromoplasts of Narcissus pseudonarcissus have been isolated in high purity and inte­ grity by a new procedure. From these chromoplasts circular DNA molecules in supercoiled form have been isolated and demonstrated by electron microscopy to have a contour length of about 44 μm (molecular weight about 92 x 106 daltons)
H, Falk, B, Liedvogel, P, Sitte
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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