Results 71 to 80 of about 2,244,972 (310)

The terminal redundant regions of bacteriophage T7 DNA: their necessity for phage production studied by the infectivity of T7 DNA after modification by various exonucleases [PDF]

, 1978
Dreiseikelmann B, Wackernagel W. The terminal redundant regions of bacteriophage T7 DNA: their necessity for phage production studied by the infectivity of T7 DNA after modification by various exonucleases. Molecular and General Genetics. 1978;159(3):321-
Dreiseikelmann, Brigitte, Wackernagel, Wilfried   +1 more
core   +1 more source

Denaturation of circular DNA: Supercoil mechanism

Physical Review E, 2011
The denaturation transition which takes place in circular DNA is analyzed by extending the Poland-Scheraga model to include the winding degrees of freedom. We consider the case of a homopolymer whereby the winding number of the double stranded helix, released by a loop denaturation, is absorbed by \emph{supercoils}.
Bar, Amir, Kabakcioglu, Alkan, Mukamel, David   +2 more
openaire   +5 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Juntos : campaña Ciudades del Caribe Circular

, 2023
¿Cómo enfrentamos la problemática de contaminación por plásticos? Lo hacemos juntos, todos los sectores: gobiernos centrales, gobiernos locales, iniciativa privada y sociedad civil.
Proyecto Caribe Circular
core  

Virological and morphological relationships in the phases of the immune control and reactivation in patients with chronic hepatitis B

Журнал инфектологии, 2016
Objective: To evaluate relationships between virological and morphological data in patients with chronic hepatitis B in phase immune control and reactivation.Materials and methods: The study involved 46 patients with chronic hepatitis B, indicators ...
I. A. Gabdrakhmanov, A. V. Semenov, Yu. V. Ostankova, K. V. Kozlov, K. V. Zhdanov, D. A. Gusev, V. S. Sukachev, D. M. Shakhmanov, S. S. Zhabrov, A. S. Peremyshlenko, Yu. I. Bulankov, A. M. Ivanov, A. A. Totolian   +12 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Study of In vitro antioxidant and DNA damage protection activity of a novel luteolin derivative isolated from Terminalia chebula

Journal of Taibah University for Science, 2019
The present study aimed to investigate the efficacy of flavonoids isolated from the fruit of Terminalia chebula against the hydrogen peroxide-induced DNA damage.
K. Soumya, Karickal R. Haridas, Jesna James, V. B. Sameer Kumar, Lincy Edatt, S. Sudheesh   +5 more
doaj   +1 more source

CSA: An efficient algorithm to improve circular DNA multiple alignment

BMC Bioinformatics, 2009
Background The comparison of homologous sequences from different species is an essential approach to reconstruct the evolutionary history of species and of the genes they harbour in their genomes.
Pereira Luísa, Fernandes Francisco, Freitas Ana T   +2 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source