Results 51 to 60 of about 3,017,680 (323)

First Insights into the Occurrence of Circular Single-Stranded DNA Genomes in Asian and African Cattle

open access: yesAnimals, 2023
Circular replicase-encoding single-stranded (CRESS) DNA viruses and other circular DNA agents are increasingly found in various samples and animals. A specific class of these agents—termed bovine meat and milk factors (BMMF)—has been supposed to act as a
Marie-Thérèse König   +7 more
doaj   +1 more source

CRISPR analysis suggests that small circular single-stranded DNA smacoviruses infect Archaea instead of humans

open access: yesNature Communications, 2019
Smacoviridae is a family of small (~2.5 Kb) CRESS-DNA (Circular Rep Encoding Single-Stranded (ss) DNA) viruses. These viruses have been found in faeces, were thought to infect eukaryotes and are suspected to cause gastrointestinal disease in humans ...
C. Díez-Villaseñor   +1 more
semanticscholar   +1 more source

Sensitive detection of circular DNAs at single-nucleotide resolution using guided realignment of partially aligned reads

open access: yesBMC Bioinformatics, 2019
Background Circular DNA has recently been identified across different species including human normal and cancerous tissue, but short-read mappers are unable to align many of the reads crossing circle junctions hence limiting their detection from short ...
Iñigo Prada-Luengo   +3 more
doaj   +1 more source

Atomic force microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in a cooperative fashion [PDF]

open access: yes, 2005
Type IB DNA topoisomerases cleave and rejoin one strand of the DNA duplex, allowing for the removal of supercoils generated during replication and transcription.
Dekker, Cees   +5 more
core   +2 more sources

The Knot Spectrum of Confined Random Equilateral Polygons

open access: yesComputational and Mathematical Biophysics, 2014
It is well known that genomic materials (long DNA chains) of living organisms are often packed compactly under extreme confining conditions using macromolecular self-assembly processes but the general DNA packing mechanism remains an unsolved problem. It
Diao Y.   +4 more
doaj   +1 more source

HBV COVALENTLY CLOSED CIRCULAR DNA AS A MARKER OF PREVALENCE OF OCCULT HEPATITIS В IN PATIENTS WITH HBV, HDV AND HCV INFECTION IN UZBEKISTAN

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. Evaluate significance of covalently closed circular DNA of hepatitis В virus as a marker for detection of occult viral hepatitis В in Uzbekistan population with hepatitis of various genesis. Materials and methods.
A. V. Semenov   +6 more
doaj   +1 more source

Temperature dependence of circular DNA topological states

open access: yes, 2009
Circular double stranded DNA has different topological states which are defined by their linking numbers. Equilibrium distribution of linking numbers can be obtained by closing a linear DNA into a circle by ligase.
Chen, Hu   +5 more
core   +1 more source

Screening for inhibitor of episomal DNA identified dicumarol as a hepatitis B virus inhibitor.

open access: yesPLoS ONE, 2019
Currently, there is no available therapy to eradicate hepatitis B virus (HBV) in chronically infected individuals. This is due to the difficulty in eliminating viral covalently closed circular (ccc) DNA, which is central to the gene expression and ...
Fumihiko Takeuchi   +16 more
doaj   +1 more source

Extrachromosomal circular DNA-based amplification and transmission of herbicide resistance in crop weed Amaranthus palmeri

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Glyphosate is a nonselective herbicide used around the globe for weed control in glyphosate-resistant (GR) and noncrop situations. The extensive and exclusive use of glyphosate has led to the evolution of herbicide resistance in many crop ...
D. Koo   +7 more
semanticscholar   +1 more source

Helix untwisting and bubble formation in circular DNA [PDF]

open access: yes, 2013
The base pair fluctuations and helix untwisting are examined for a circular molecule. A realistic mesoscopic model including twisting degrees of freedom and bending of the molecular axis is proposed.
Bates A. D.   +3 more
core   +2 more sources

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