Frontiers in ImmunologyMacrophages execute host defense against pathogens by releasing extracellular traps (METs) composed of DNA meshwork and antimicrobial proteins. Although MET-mediated pathogen immobilization is well documented, the induction mechanisms of MET generation ...
Taoxun Zhou +7 more
doaj +1 more source
Improved PCR-Based Detection of Soil Transmitted Helminth Infections Using a Next-Generation Sequencing Approach to Assay Design. [PDF]
PLoS Neglected Tropical Diseases, 2016 BACKGROUND:The soil transmitted helminths are a group of parasitic worms responsible for extensive morbidity in many of the world's most economically depressed locations.
Nils Pilotte +6 more
doaj +1 more source
Molecular Epidemiology of Ascariasis: A Global Perspective on the Transmission Dynamics of Ascaris in People and Pigs [PDF]
, 2014 Background The roundworm Ascaris lumbricoides infects 0.8 billion people worldwide, and Ascaris suum infects innumerable pigs across the globe. The extent of natural cross-transmission of Ascaris between pig and human hosts in different geographical ...
Bendall, R P +6 more
core +3 more sources
Daily Preventive Zinc Supplementation Decreases Lymphocyte and Eosinophil Concentrations in Rural Laotian Children from Communities with a High Prevalence of Zinc Deficiency: Results of a Randomized Controlled Trial. [PDF]
, 2020 BACKGROUND:Zinc deficiency impairs immune function and is common among children in South-East Asia. OBJECTIVES:The effect of zinc supplementation on immune function in young Laotian children was investigated.
Andreini +54 more
core +2 more sources
Chalone-like inhibition of DNA synthesis in helminths.
Folia parasitologica, 1985 Chalone-like inhibitory activity was found in extracts from tissues of Taenia crassiceps cysticercus and tissues of adult Ascaris suum. The inhibitory effects were partially species nonspecific: The extracts from T. crassiceps larvae inhibit both T. crassiceps and Mesocestoides corti larvae DNA synthesis. Extracts from A. suum, however, inhibit only T.
K, Kudrna, J, Prokopic
openaire +1 more source
Whipworms in humans and pigs: origins and demography [PDF]
, 2016 © 2016 Hawash et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in ...
Al-Jubury, A +9 more
core +2 more sources
EBioMedicine, 2022 Summary: Background: Alveolar echinococcosis (AE), which is caused by larval Echinococcus multilocularis, is one of the world's most dangerous neglected diseases. Currently, no fully effective treatments are available to cure this disease.
Zhongli Liu +12 more
doaj +1 more source
The tapeworm interactome: inferring confidence scored protein-protein interactions from the proteome of Hymenolepis microstoma [PDF]
, 2020 BACKGROUND: Reference genome and transcriptome assemblies of helminths have reached a level of completion whereby secondary analyses that rely on accurate gene estimation or syntenic relationships can be now conducted with a high level of confidence ...
James, Katherine, Olson, Peter D.
core +2 more sources
Development and validation of real-time PCR for rapid detection of Mecistocirrus digitatus. [PDF]
PLoS ONE, 2013 Hematophagous activity of Mecistocirrus digitatus, which causes substantial blood and weight loss in large ruminants, is an emerging challenge due to the economic loss it brings to the livestock industry.
Subhra Subhadra +2 more
doaj +1 more source
Diagnosis of \u3cem\u3eSchistosoma mansoni\u3c/em\u3e without the Stool: Comparison of Three Diagnostic Tests to Detect \u3cem\u3eSchiostosoma mansoni\u3c/em\u3e Infection from Filtered Urine in Zambia [PDF]
, 2013 Diagnosis for intestinal Schistosoma mansoni lacks sensitivity and is arduous to conduct. The standard diagnostic tests, Kato-Katz (KK) and circulating cathodic antigen (CCA) both lack sensitivity and with KK, require obtaining, transporting, and ...
Lodh, Nilanjan +3 more
core +1 more source