Results 141 to 150 of about 3,128,275 (354)
Molecular Genetics & Genomic Medicine, 2019 Background Profiling of mitochondrial DNA is surely to provide valuable investigative clues for forensic cases involving highly degraded specimens or complex maternal lineage kinship determination.
Qiong Lan +6 more
doaj +1 more source
Novel Insights into Mitochondrial DNA: Mitochondrial Microproteins and mtDNA Variants Modulate Athletic Performance and Age-Related Diseases. [PDF]
Genes (Basel), 2023 Kumagai H +6 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Measuring AMP‐activated protein kinase (AMPK) activity in vitro is crucial for testing AMPK activators or inhibitors with therapeutic potential. Here, we report an enzyme‐linked immunosorbent assay (ELISA)‐based AMPK activity assay with simple steps and high sensitivity, which offers a simple, robust, and cost‐effective alternative to traditional ...
Trezze P. Nguyen, Shangze Lyu, Yang Liu
wiley +1 more source
Mitochondrial Quality Control in Age-Related Pulmonary Fibrosis. [PDF]
, 2020 Idiopathic pulmonary fibrosis (IPF) is age-related interstitial lung disease of unknown etiology. About 100,000 people in the U.S have IPF, with a 3-year median life expectancy post-diagnosis.
Cuevas-Mora, Karina +2 more
core +1 more source
Early Plasma Nuclear DNA, Mitochondrial DNA, and Nucleosome Concentrations Are Associated With Acute Kidney Injury in Critically Ill Trauma Patients. [PDF]
Crit Care Explor, 2022 Faust HE +13 more
europepmc +1 more source
Mitochondrial DNA and Genetic Disease [PDF]
Developmental Medicine & Child Neurology, 1988 AbstractSince the human mitochondrial genome was characterised and sequenced in 1981(1), it has been viewed as the likely site of genetic diseases showing a maternal inheritance pattern and associated with defects of the respiratory chain, such as the mitochondrial myopathies (MMs)†(2).
openaire +7 more sources
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
Progression of myopathology in Kearns-Sayre syndrome [PDF]
, 1992 We report on the progression of myopathology by comparing two biopsies from a patient with a Kearns-Sayre-Syndrome. The first biopsy was taken in 1979 and showed 10% ragged-red fibers.
B. Meurers +11 more
core +1 more source
Mitochondrial fusion is required for regulation of mitochondrial DNA replication
PLoS Genetics, 2019 Mitochondrial dynamics is an essential physiological process controlling mitochondrial content mixing and mobility to ensure proper function and localization of mitochondria at intracellular sites of high-energy demand.
Eduardo Silva Ramos +12 more
semanticscholar +1 more source
About the Number of Base Substitutions Between Humans and Common Chimpanzees [PDF]
arXiv, 2010 Humans and chimpanzees are believed to have shared a common ancestor about 6 million years ago. Here using a new distance measure called the Jump distance, we calculate the number of base substitutions that might have occurred in the mitochondrial DNA during these 6 million years.
arxiv