Results 221 to 230 of about 3,292,865 (329)

An Allele of Glutamate Formiminotransferase Triggers 5‐Methyl‐Tetrahydrofolate‐to‐MeFox Conversion and Facilitates Folate Biofortification in Maize

Advanced Science, EarlyView.
This work demonstrates the distinct roles of the glutamate formiminotransferase (GFT) enzyme in plants. The GFT triggers the conversion of 5‐methyl‐tetrahydrofolate to MeFox in plants, a process distinct from its role as a formiminotransferase in mammals.
Tong Lian, Wenzhu Guo, Yanjing Wang, Weiwei Wen, Weixuan Wang, Ling Jiang, Qiuju Liang, Ji'an Liu, Haijun Liu, Yuan Xue, Lixu Pan, Qiaoquan Liu, Ping Yin, Delin Zhang, Jianbing Yan, Chunyi Zhang   +15 more
wiley   +1 more source

Efficient extracellular expression and rapid screening of human-like recombinant gelatin in Komagataella phaffii. [PDF]

Sci Rep
Song X, Wang Y, Kan K, Chai Z, Wang L, Li M, Liu Z.   +6 more
europepmc   +1 more source

Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine.

Proceedings of the National Academy of Sciences of the United States of America, 1998
M. Sedegah, T. Jones, M. Kaur, R. Hedstrom, P. Hobart, John A. Tine, S. Hoffman   +6 more
semanticscholar   +1 more source

M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy With Comorbid Traits

Advanced Science, EarlyView.
Genes associated with endometriosis risk are highly expressed in M2 macrophages, particularly ligands IL1A and IL1B. Endometrial‐type epithelium and stroma are likely recipients of these ligands. While IL1B treatment disturbs epithelial organization, blockage of the signaling results in a dose‐dependent decrease in spontanesous and evoked pain, reduces
Soledad Ochoa, Fernanda S. Rasquel‐Oliveira, Brett McKinnon, Marcela Haro, Sugarniya Subramaniam, Pak Yu, Simon Coetzee, Michael S. Anglesio, Kelly N. Wright, Raanan Meyer, Anne E. Porter, Caroline E. Gargett, Sally Mortlock, Grant W. Montgomery, Michael S. Rogers, Kate Lawrenson   +15 more
wiley   +1 more source

Insect cell expression system: advances in applications, engineering strategies, and bioprocess development. [PDF]

J Biol Eng
Huang N, Wei Y, Li J.
europepmc   +1 more source

FBXO44 Regulates FOXP1 Degradation Through AURKA‐Dependent Phosphorylation to Promote Colorectal Cancer Progression

Advanced Science, EarlyView.
FBXO44 promotes colorectal cancer progression by targeting FOXP1 for ubiquitin‐mediated degradation. This study reveals a phosphorylation‐dependent mechanism involving AURKA and highlights the FBXO44/FOXP1/Cyclin E2 axis as a potential therapeutic target in colorectal cancer.
Hongxu Nie, Hengjie Xu, Sheng Yang, Chuanxin Tian, Tuo Wang, Chi Jin, Zhihao Chen, Xiaowei Wang, Junwei Tang, Yifei Feng, Yueming Sun   +10 more
wiley   +1 more source

Highly efficient gene editing of <i>Feline herpesvirus 1</i> using CRISPR/Cas9 combined with FACS. [PDF]

Front Cell Infect Microbiol
Wang HM, Xu SJ, Cai BY, Qiu WY, Lu H, Tang YD.   +5 more
europepmc   +1 more source

Transcriptome‐Wide Association Uncovers LncRNAs Controlling Seed Weight in Soybean

Advanced Science, EarlyView.
This study employs transcriptome‐wide association studies (TWAS) to identify 201 long non‐coding RNAs (lncRNAs) associated with seed weight. Expression quantitative trait locus (eQTL) analysis reveals dynamic and static regulatory variants controlling lncRNA expression across development.
Xiang Wang, Xinyu Jiang, Xiaobo Yuan, Zhipeng Zhou, Zhenwei Zhao, Longfei Wang, Wu Jiao, Wenxue Ye, Qingxin Song   +8 more
wiley   +1 more source

The Production of Recombinant Azurin from <i>Pseudomonas aeruginosa</i> and Its Ability to Induce Apoptosis in Various Breast Cancer Cell Lines. [PDF]

Int J Mol Sci
Kowalczyk T, Merecz-Sadowska A, Synowiec E, Śliwiński T, Piekarski J, Szemraj J, Mori M, Rijo P, Sitarek P.   +8 more
europepmc   +1 more source

Emodin Alleviates Sepsis‐Induced Multiorgan Damage by Inhibiting NETosis through Targeting Neutrophils BCL‐10

Advanced Science, EarlyView.
Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu, Yumeng Yan, Meiling Zheng, Mina Zhang, Tengfei Chen, Zhicheng Qu, Yinglu Bai, Shuwen Zhang, Chunming Zhao, Yifan Shi, Yan Lin, Ning Wang, Yunjing Bai, Yating Zhai, Zhaofang Bai, Wei Guo, Qingquan Liu   +16 more
wiley   +1 more source