Results 31 to 40 of about 3,265,618 (328)
APLF (C2orf13) is a novel component of poly(ADP-ribose) signaling in mammalian cells [PDF]
, 2008 APLF is a novel protein of unknown function that accumulates at sites of chromosomal DNA strand breakage via forkhead-associated (FHA) domain-mediated interactions with XRCC1 and XRCC4.
Caldecott, Keith W +4 more
core +3 more sources
Impact of PNKP mutations associated with microcephaly, seizures and developmental delay on enzyme activity and DNA strand break repair [PDF]
, 2012 Microcephaly with early-onset, intractable seizures and developmental delay (MCSZ) is a hereditary disease caused by mutations in polynucleotide kinase/phosphatase (PNKP), a DNA strand break repair protein with DNA 5'-kinase and DNA 3'-phosphatase ...
Alexandra K. Walker +41 more
core +1 more source
Frontiers in Bioengineering and Biotechnology, 2019 Infectious diseases, along with cancers, are among the main causes of death among humans worldwide. The production of therapeutic proteins for treating diseases at large scale for millions of individuals is one of the essential needs of mankind.
N. Tripathi, A. Shrivastava
semanticscholar +1 more source
Claspin and the Activated Form of ATR-ATRIP Collaborate in the Activation of Chk1 [PDF]
, 2004 Claspin is necessary for the ATR-dependent activation of Chk1 in Xenopus egg extracts containing incompletely replicated DNA. ATR possesses a regulatory partner called ATRIP. We have studied the respective roles of ATR-ATRIP and Claspin in the activation
Dunphy, William G. +2 more
core +1 more source
Recombinant DNA production of spider silk proteins
Microbial Biotechnology, 2013 Spider dragline silk is considered to be the toughest biopolymer on Earth due to an extraordinary combination of strength and elasticity. Moreover, silks are biocompatible and biodegradable protein‐based materials.
Olena S Tokareva +3 more
semanticscholar +1 more source
Construction of Recombinant Vaccinia Viruses Using PUV-Inactivated Virus as a Helper
BioTechniques, 2001 Recombinant vaccinia viruses (VVs) are widely used as expression vectors in molecular biology and immunology and are now under evaluation for gene therapy.
Tatyana M. Timiryasova +3 more
doaj +1 more source
Expression of functional recombinant human tissue transglutaminase (TG2) using the bac-to-bac baculovirus expression system [PDF]
, 2016 Purpose: Tissue transglutaminase (TG2) is a unique multifunctional enzyme. The enzyme possesses enzymatic activities such as transamidation/crosslinking and non-enzymatic functions such as cell migration and signal transduction.
Azari, S., Kalhor, H.R., Yazdani, Y.
core +2 more sources
International Journal of Mycobacteriology, 2017 Background: We aimed to study the antigen-specific antibody responses in mice immunized with recombinant DNA vaccines constructs of pUMVC6 and pUMVC7, containing RD1 and RD9 genes of Mycobacterium tuberculosis.
Shumaila N. M. Hanif, A S Mustafa
doaj +1 more source
Coherent band pathways between knots and links
, 2014 We categorise coherent band (aka nullification) pathways between knots and 2-component links. Additionally, we characterise the minimal coherent band pathways (with intermediates) between any two knots or 2-component links with small crossing number.
Buck, Dorothy, Ishihara, Kai
core +1 more source
Expression of the murine cytomegalovirus glycoprotein H by recombinant vaccinia virus [PDF]
, 1994 The sequence of the gene encoding glycoprotein H (gH) of murine cytomegalovirus (MCMV) strain Smith was determined and compared with the sequence of the gH of MCMV strain K181. Transcriptional analysis showed that gH is encoded by a large mRNA of 5.0 kb,
Koszinowski, Ulrich H. +4 more
core +1 more source