Results 31 to 40 of about 2,933,423 (207)

DNA looping: the consequences and its control [PDF]

Curr. Opin. Struct. Biol. 16, 344-350 (2006), 2006
The formation of DNA loops by proteins and protein complexes is ubiquitous to many fundamental cellular processes, including transcription, recombination, and replication. Here we review recent advances in understanding the properties of DNA looping in its natural context and how they propagate to the cellular behavior through gene regulation.
arxiv   +1 more source

Recent Developments in Bioprocessing of Recombinant Proteins: Expression Hosts and Process Development

Frontiers in Bioengineering and Biotechnology, 2019
Infectious diseases, along with cancers, are among the main causes of death among humans worldwide. The production of therapeutic proteins for treating diseases at large scale for millions of individuals is one of the essential needs of mankind.
N. Tripathi, A. Shrivastava
semanticscholar   +1 more source

Complementary Theory of Evolutionary Genetics [PDF]

arXiv, 2021
This theory seeks to define species and to explore evolutionary forces and genetic elements in speciation and species maintenance. The theory explains how speciation and species maintenance are caused by natural selection acting on non-Mendelian and Mendelian variation, respectively. The emergence and maintenance of species as groups of populations are
arxiv  

Recombinant DNA production of spider silk proteins

Microbial Biotechnology, 2013
Spider dragline silk is considered to be the toughest biopolymer on Earth due to an extraordinary combination of strength and elasticity. Moreover, silks are biocompatible and biodegradable protein‐based materials.
Olena S Tokareva, V. Michalczechen-Lacerda, E. Rech, D. Kaplan   +3 more
semanticscholar   +1 more source

Construction of Recombinant Vaccinia Viruses Using PUV-Inactivated Virus as a Helper

BioTechniques, 2001
Recombinant vaccinia viruses (VVs) are widely used as expression vectors in molecular biology and immunology and are now under evaluation for gene therapy.
Tatyana M. Timiryasova, Bing Chen, Nadja Fodor, Istvan Fodor   +3 more
doaj   +1 more source

Humoral immune responses in mice immunized with region of difference DNA vaccine constructs of pUMVC6 and pUMVC7

International Journal of Mycobacteriology, 2017
Background: We aimed to study the antigen-specific antibody responses in mice immunized with recombinant DNA vaccines constructs of pUMVC6 and pUMVC7, containing RD1 and RD9 genes of Mycobacterium tuberculosis.
Shumaila N. M. Hanif, A S Mustafa
doaj   +1 more source

Phase 1 safety and immunogenicity testing of DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particles.

Journal of Infectious Diseases, 2011
BACKGROUND Recombinant DNA and modified vaccinia virus Ankara (rMVA) vaccines represent a promising approach to an HIV/AIDS vaccine. This Phase 1 clinical trial compared the safety and immunogenicity of a rMVA vaccine administered with and without DNA ...
P. Goepfert, M. Elizaga, A. Sato, L. Qin, M. Cardinali, C. Hay, J. Hural, S. DeRosa, O. Defawe, G. Tomaras, D. Montefiori, Yongxian Xu, L. Lai, S. Kalams, L. Baden, S. Frey, W. Blattner, L. Wyatt, B. Moss, H. Robinson   +19 more
semanticscholar   +1 more source

QTL-seq: rapid mapping of quantitative trait loci in rice by whole genome resequencing of DNA from two bulked populations.

The Plant Journal, 2013
The majority of agronomically important crop traits are quantitative, meaning that they are controlled by multiple genes each with a small effect (quantitative trait loci, QTLs).
H. Takagi, A. Abe, Kentaroh Yoshida, S. Kosugi, S. Natsume, Chikako Mitsuoka, Aiko Uemura, Hiroe Utsushi, Muluneh Tamiru, Shohei Takuno, H. Innan, L. Cano, S. Kamoun, R. Terauchi   +13 more
semanticscholar   +1 more source

Evaluation of virulence genes in Proteus strains isolated from diabetic foot infections and urinary tract infections

Journal of Infection in Developing Countries
Introduction: Proteus species are frequently isolated from urinary tract infections (UTIs) and diabetic foot infections (DFIs). We aimed to evaluate the presence of virulence genes in P. mirabilis and P.
Ruth M Phiri, Mustafa Bülent Ertuğrul, Bülent Bozdoğan, Tuğrul Hoşbul   +3 more
doaj   +1 more source

Construction and Immunogenicity Testing of Salmonella, STM1 Vaccine Vector Expressing HIV-1 Antigen

Indonesian Journal of Biotechnology, 2009
Objective of this study: to determine the ability of Salmonella enterica serovar Typhimurium STM1 as a delivery vehicle for the HIV p24 gene and HIV env gene.
Endang Winiati Bachtiar, Peter Smooker, Peter J Coloe   +2 more
doaj   +1 more source