Results 71 to 80 of about 2,933,423 (207)
DNA damage, homology-directed repair, and DNA methylation. [PDF]
PLoS Genetics, 2007 To explore the link between DNA damage and gene silencing, we induced a DNA double-strand break in the genome of Hela or mouse embryonic stem (ES) cells using I-SceI restriction endonuclease. The I-SceI site lies within one copy of two inactivated tandem
Concetta Cuozzo +13 more
doaj +1 more source
Journal of Immunology, 1998 Unmethylated CpG dinucleotides in bacterial DNA or synthetic oligodeoxynucleotides (ODN) cause B cell proliferation and Ig secretion, monocyte cytokine secretion, and activation of NK cell lytic activity and IFN-gamma secretion in vivo and in vitro.
H. Davis +5 more
semanticscholar +1 more source
Pesquisa Veterinária Brasileira, 2013 A thymidine kinase (tk)-deleted bovine herpesvirus 5 (BoHV-5tkΔ) was previously shown to establish latent infection and reactivate - even poorly - in a sheep model (Cadore et al. 2013). As TK-negative alphaherpesviruses are unlike to reactivate in neural
Gustavo C. Cadore +4 more
doaj +1 more source
Coherent band pathways between knots and links [PDF]
arXiv, 2014 We categorise coherent band (aka nullification) pathways between knots and 2-component links. Additionally, we characterise the minimal coherent band pathways (with intermediates) between any two knots or 2-component links with small crossing number. We demonstrate these band surgeries for knots and links with small crossing number.
arxiv
Nonlinear waves in double-stranded DNA [PDF]
arXiv, 2004 We propose a nonlinear model derived from first principles, to describe bubble dynamics of DNA. Our model equations include a term derived from the dissipative effect of intermolecular vibrational modes. Such modes are excited by the propagating bubble, and we term it "curvature dissipation".
arxiv
Recombinant vesicular stomatitis viruses from DNA.
Proceedings of the National Academy of Sciences of the United States of America, 1995 We assembled a DNA clone containing the 11,161-nt sequence of the prototype rhabdovirus, vesicular stomatitis virus (VSV), such that it could be transcribed by the bacteriophage T7 RNA polymerase to yield a full-length positive-strand RNA complementary ...
N. Lawson +3 more
semanticscholar +1 more source
Plasmid DNA-based Alphavirus Vaccines
Vaccines, 2019 Alphaviruses have been engineered as vectors for high-level transgene expression. Originally, alphavirus-based vectors were applied as recombinant replication-deficient particles, subjected to expression studies in mammalian and non-mammalian cell lines,
Kenneth Lundstrom
doaj +1 more source
Bioinform., 2004 SUMMARY TOPALi is a new Java graphical analysis application that allows the user to identify recombinant sequences within a DNA multiple alignment (either automatically or via manual investigation).
Iain Milne +5 more
semanticscholar +1 more source
Cloning of cDNA Encoding GRA1 Protein of Tachyzoite Toxoplasma Gondii Local Isolate
Indonesian Journal of Biotechnology, 2015 Gene encoding GRA1 protein is potent DNA-vaccine candidate against toxoplasmosis. The aim of the researchwas to clone the gene encoding GRA1 protein of tachyzoite Toxoplasma gondii local isolate by DNA recombinanttechnology.
Erma Sulistyaningsih +3 more
doaj
PLoS ONE, 2017 DNA polymerases are present in all organisms and are important enzymes that synthesise DNA molecules. They are used in various fields of science, predominantly as essential components for in vitro DNA syntheses, known as PCR.
Marcin Olszewski +3 more
doaj +1 more source