Results 261 to 270 of about 2,640,580 (326)

RNA G-quadruplexes promote codon repeat-associated ribosomal frameshifting in human genes. [PDF]

Nucleic Acids Res
Li X, Li Z, Zhou Y, Gong S, Chen Z, Li J, Guo M, Gu X, Li F, Wei J, Zhong T, Yin T, Li T, Xing Y, Yang X, Xu L, Lai F, Dang Y, Ren G.   +18 more
europepmc   +1 more source

Improved Messenger RNA Stability and Biocompatibility Through Self‐Gelatinizable Nucleic Acids

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Recent advances in the chemical synthesis and modification of messenger RNA (mRNA) have generated growing interest in mRNA‐based therapeutics. However, the inherent instability of mRNA in vivo and during storage remains a major challenge, requiring the development of safe and effective delivery systems.
Takumi Tanifuji, Kosuke Kusamori, Chihiro Tanaka, Hideki Sakai, Shoko Itakura, Makiya Nishikawa   +5 more
wiley   +1 more source

Comparison of Metabarcoding and Shotgun Sequencing Confirms the Relevance of Chloroplastic rRNA Genes to Assess Community Structure of Lake Phytoplankton. [PDF]

Mol Ecol Resour
Lemonnier C, Alric B, Domaizon I, Rimet F.   +3 more
europepmc   +1 more source

Enhancing CHO cell recombinant protein production using a perfusion‐directed host evolution approach

Biotechnology Progress, EarlyView.
Abstract Clonally derived cell lines generated from Chinese hamster ovary (CHO) cells encounter numerous stressors when cultured in high‐intensity perfusion bioreactors leading to poor process performance. To circumvent this, the ability of CHO cells to adapt to different culture environments was exploited. Here host cells were selected in the presence
Peter Amaya, Rajesh K. Mistry, Susie Sou, Sonja Hess, Bijay Khanal, Zayla Schaeffer, Jie Zhu, Lina Chakrabarti   +7 more
wiley   +1 more source

How Early-Life Programming During Embryogenesis Imprints Cellular Memory. [PDF]

Int J Mol Sci
Alfian NF, Uechi K, Morishita Y, Sato K, Yui M, Jharna JF, Bari MW, Ishiyama S, Mochizuki K, Kishigami S.   +9 more
europepmc   +1 more source

Association Between D‐amino Acids in Natto (fermented soybeans) and Kidney Dysfunction

ChemFoodChem, EarlyView.
XX XX ABSTRACT In this study, we examined clinical and cohort data to explore the potential renoprotective effects of natto (fermented soybeans) consumption and its relationship with D‐amino acids. In a clinical study, ten healthy adults consumed one 40‐g pack of natto three times in a single day, and plasma and urine samples were collected 1 h and 24 ...
Yusuke Nakade, Tadashi Toyama, Akinori Hara, Shigefumi Okamoto, Hiroaki Masuoka, Wataru Suda, Masashi Mita, Yuna Miyajima, Keishi Mizuguchi, Takeo Yuno, Hiroka Yamazaki, Hiroki Ohtani, Hoang Thuy Linh, Megumi Oshima, Miho Shimizu, Norihiko Sakai, Hiromasa Tsujiguchi, Hiroyuki Nakamura, Yasunori Iwata, Takashi Wada   +19 more
wiley   +1 more source

Beyond Hematologic Malignancies: Colorectal Cancer as a Solid Tumor Manifestation of Inherited Bone Marrow Failure Syndromes. [PDF]

Int J Mol Sci
Cagliano S, Potenza M, La Vecchia M, Ellis SR, Dianzani I, Aspesi A.   +5 more
europepmc   +1 more source

Recent Advances in Chemical Probing Strategies for RNA Structure Determination in Vivo

Chemistry – A European Journal, EarlyView.
This Review illustrates how structural probes combined with advanced sequencing technologies are revolutionizing our ability to map RNA structures and interactions within living cells. It highlights the development of innovative strategies tailored to probe RNA structures in particular biological contexts.
Maryana Yarshova, Jieyu Zhao, Chun Kit Kwok   +2 more
wiley   +1 more source

Hidden hemoplasma species within the "Candidatus Mycoplasma haemominutum" lineage in Thai cats revealed by analyses of two independent genetic markers. [PDF]

Parasit Vectors
Thongmeesee K, Bui TTH, Narapakdeesakul D, Kamkong P, Thanee S, Aung A, Sri-In C, Wechtaisong W, Tiwananthagorn S, Colella V, Tiawsirisup S.   +10 more
europepmc   +1 more source

Bottom‐up Strategies for Generating Polymer Protocells That Mimic Cellular Communication

Chemistry – A European Journal, EarlyView.
This review focuses on polymeric protocells produced using a bottom‐up approach. Polymer‐based assemblies guarantee stability and designability by adjusting the properties of the amphiphilic copolymers used. The review covers protocell architectures, production, and their intra‐ and intercellular communication mechanisms.
Gloria Saorin, Xinan Huang, Voichita Mihali, Cornelia G. Palivan   +3 more
wiley   +1 more source