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Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus [PDF]
Epigenetics, 2023 The human ribosomal DNA (rDNA) copy number (CN) has been challenging to analyse, and its sequence has been excluded from reference genomes due to its highly repetitive nature. The 45S rDNA locus encodes essential components of the cell, nevertheless rDNA
Aleem Razzaq +4 more
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Genome-wide DNA methylation profiles and ribosomal DNA copy number at birth [PDF]
EpigeneticsRibosomal DNA copy number (rDNAcn) and DNA methylation are important modulators of the human genome, both studied in relation to overall cellular function, biological ageing, and disease development.
Kathrin Barth +5 more
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RNA polymerase I mutant affects ribosomal RNA processing and ribosomal DNA stability [PDF]
RNA BiologyTranscription is a major contributor to genomic instability. The ribosomal RNA (rDNA) gene locus consists of a head-to-tail repeat of the most actively transcribed genes in the genome.
Christophe Normand +7 more
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CX-5461 Preferentially Induces Top2α-Dependent DNA Breaks at Ribosomal DNA Loci [PDF]
BiomedicinesWhile genotoxic chemotherapeutic agents are among the most effective tools to combat cancer, they are often associated with severe adverse effects caused by indiscriminate DNA damage in non-tumor tissue as well as increased risk of secondary ...
Donald P. Cameron +8 more
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Guangdong nongye kexue, 2022 【Objective】The study was carried out to explore the molecular identification of Wuzhi No. 2 (original name: Zizhi S2), a new cultivar of Ganoderma sp., by rDNA-ITS sequence analysis and ITS2 secondary structure model.【Method】The sequences of Wuzhi No.
Liyi ZHONG +3 more
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DNA replication stress restricts ribosomal DNA copy number. [PDF]
PLoS Genetics, 2017 Ribosomal RNAs (rRNAs) in budding yeast are encoded by ~100-200 repeats of a 9.1kb sequence arranged in tandem on chromosome XII, the ribosomal DNA (rDNA) locus.
Devika Salim +6 more
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Isolation and study of morphology and phylogeny of arbuscular mycorrhizal fungi coexisting with the roots of some medicinal plants in Kerman province [PDF]
مجله بیوتکنولوژی کشاورزی, 2020 Objective Plants that have a symbiotic relationship with arbuscular mycorrhizal fungi (AMF) compared with non-mycorrhizal plants have a higher ability to resist against various biotic and abiotic environmental stresses such as drought, salinity, pests ...
Eidi bazgir +3 more
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DNA Binding by the Ribosomal DNA Transcription Factor Rrn3 Is Essential for Ribosomal DNA Transcription [PDF]
Journal of Biological Chemistry, 2013 The human homologue of yeast Rrn3 is an RNA polymerase I-associated transcription factor that is essential for ribosomal DNA (rDNA) transcription. The generally accepted model is that Rrn3 functions as a bridge between RNA polymerase I and the transcription factors bound to the committed template. In this model Rrn3 would mediate an interaction between
Ann, Stepanchick +5 more
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Heterogeneity of Pumpkin Ribosomal DNA [PDF]
Plant Physiology, 1983 The ribosomal DNA (rDNA) of Cucurbita pepo L. has been found to consist of tandemly arrayed repeat units, most of which are 10 kilobases in length. Thirty-six repeat units, cloned into the HindIII site of pACYC 177, fall into seven classes which differ from each other in length and/or nucleotide sequence.
A, Siegel, K, Kolacz
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Animal Cells and Systems, 2021 The harmful jellyfish Cyanea nozakii Kishinouye has frequently occurred on Korean coasts, and its blooms have caused serious ecological and economic damages. DNA sequences of the C. nozakii for molecular detection and discrimination are relatively scarce.
Buhari Lawan Muhammad +2 more
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