Next generation sequencing analysis reveals a relationship between rDNA unit diversity and locus number in Nicotiana diploids [PDF]
, 2012 © 2012 Matyášek et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Fulnecek, J +7 more
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Ribosomal DNA magnification in Saccharomyces cerevisiae [PDF]
Journal of Bacteriology, 1978 Strains monosomic for chromosome I of Saccharomyces cerevisiae contain 25 to 35% fewer rRNA genes than do normal diploid strains. When these strains are repeatedly subcultured, colonies are isolated that have magnified their number of rRNA genes to the diploid amount while remaining monosomic for chromosome I.
D B, Kaback, H O, Halvorson
openaire +2 more sources
Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation
Nature Communications, 2020 DNA double-strand breaks in ribosomal DNA repeats is associated with repression of ribosomal RNA synthesis. Here the authors reveal a cooperation between TOPBP1 and Treacle in the signaling cascade that triggers transcriptional inhibition and nucleolar ...
Clémence Mooser +15 more
doaj +1 more source
The replicative lifespan-extending deletion of SGF73 results in altered ribosomal gene expression in yeast. [PDF]
, 2017 Sgf73, a core component of SAGA, is the yeast orthologue of ataxin-7, which undergoes CAG-polyglutamine repeat expansion leading to the human neurodegenerative disease spinocerebellar ataxia type 7 (SCA7).
Garza, Renee M +6 more
core +2 more sources
Ribosomal DNA copy number loss and sequence variation in cancer
PLoS Genetics, 2017 Ribosomal DNA is one of the most variable regions in the human genome with respect to copy number. Despite the importance of rDNA for cellular function, we know virtually nothing about what governs its copy number, stability, and sequence in the ...
Baoshan Xu +9 more
semanticscholar +1 more source
PCR amplification of a long rDNA segment with one primer pair in agriculturally important nematodes
Journal of Nematology, 2019 Ribosomal DNA has been a reliable source of taxonomic and phylogenetic markers due to its high copy number in the genome and stable variation with few polymorphisms due to the homogenizing effect of concerted evolution.
Carta L. K., Li S.
doaj +1 more source
SMN-deficient cells exhibit increased ribosomal DNA damage
Life Science Alliance, 2022 SMN deficiency leads to elevated ribosomal DNA damage that results in impaired ribosomal RNA synthesis and translation and is accompanied by a motor neuron-specific down-regulation of DDX21 protein.
Evangelia Karyka +13 more
doaj +1 more source
Ribosomal small subunit sequence diversity of Scutellospora within single spores and roots of bluebell from a woodland community. [PDF]
, 1999 Roots of bluebell (Hyacinthoides nonscripta) were sampled from a woodland in Yorkshire,UK and spores of an arbuscular mycorrhizal fungus Scutellospora sp., were obtained from the surrounding soil.
Clapp, J.P., Fitter, A.H., Young, J.P.W.
core +1 more source
Memorias do Instituto Oswaldo Cruz, 2004 A ribosome association factor (AF) was isolated from the yeast Sacchharomyces cerevisiae. Partial amino acid sequence of AF was determined from its fragment of 25 kDa isolated by treating AF with 2-(2-nitrophenylsulfenyl)-3-methyl-3'-Bromoindolenine ...
Heriberto Correia +5 more
doaj +1 more source
Taxonomy of anaerobic digestion microbiome reveals biases associated with the applied high throughput sequencing strategies [PDF]
, 2018 In the past few years, many studies investigated the anaerobic digestion microbiome by means of 16S rRNA amplicon sequencing. Results obtained from these studies were compared to each other without taking into consideration the followed procedure for ...
Angelidaki, Irini +4 more
core +3 more sources