Results 51 to 60 of about 2,892,023 (342)
Superresolution microscopy reveals linkages between ribosomal DNA on heterologous chromosomes
Journal of Cell Biology, 2019 Potapova et al. use superresolution microscopy to describe linkages between ribosomal DNA on heterologous human chromosomes whose formation depends on the transcription factor UBF and topoisomerase II.
T. Potapova +6 more
semanticscholar +1 more source
Early life stress inhibits expression of ribosomal RNA in the developing hippocampus. [PDF]
PLoS ONE, 2014 Children that are exposed to abuse or neglect show abnormal hippocampal function. However, the developmental mechanisms by which early life stress (ELS) impairs normal hippocampal development have not been elucidated. Here we propose that exposure to ELS
Lan Wei, Jin Hao, Arie Kaffman
doaj +1 more source
The Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like Episode Syndrome-associated Human Mitochondrial tRNALeu(UUR) Mutation Causes Aminoacylation Deficiency and Concomitant Reduced Association of mRNA with Ribosomes [PDF]
, 2000 The pathogenetic mechanism of the mitochondrial tRNALeu(UUR) A3243G transition associated with the mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome has been investigated in transmitochondrial cell lines ...
Attardi, Giuseppe +4 more
core +1 more source
Keeping ribosomal DNA intact: a repeating challenge
Chromosome Research, 2018 More than half of the human genome consists of repetitive sequences, with the ribosomal DNA (rDNA) representing two of the largest repeats. Repetitive rDNA sequences may form a threat to genomic integrity and cellular homeostasis due to the challenging ...
Daniël O. Warmerdam, R. Wolthuis
semanticscholar +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
PLoS ONE, 2009 Bacterial 16S ribosomal DNA (rDNA) amplicons have been widely used in the classification of uncultured bacteria inhabiting environmental niches. Primers targeting conservative regions of the rDNAs are used to generate amplicons of variant regions that ...
Yong Wang, P. Qian
semanticscholar +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Evaluation of COI and ITS2 sequences ability to distinguish Lysiphlebus fabarum and Lysiphlebus confusus (Hymenoptera: Aphidiidae) [PDF]
نامه انجمن حشرهشناسی ایران, 2012 All wasp species in the genus Lysiphlebus Förster are solitary endoparasitoids of aphids andconsidered a taxonomically difficult group. In this study a part of COI and ITS2 was used to distinguishtwo closely related species L.
M. M. Sohani +3 more
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Frontiers in Genetics, 2018 Introduction: The multi-copied genes coding for the human 18, 5.8, and 28S ribosomal RNA (rRNA) are located in five pairs of acrocentric chromosomes forming so-called rDNA.
Elena M. Malinovskaya +7 more
doaj +1 more source
Frontiers in Oncology, 2022 Next-generation sequencing and bioinformatics analyses have clearly revealed the roles of mitochondrial ribosomal genes in cancer development. Mitochondrial ribosomes are composed of three RNA components encoded by mitochondrial DNA and 82 specific ...
Shunchao Bao +6 more
doaj +1 more source