Results 61 to 70 of about 317,056 (255)

Cloning and sequencing of the complicated rDNA gene family of Bos taurus

Czech Journal of Animal Science, 2006
The rDNA genes coding for ribosomal RNA (rRNA) in animals are repeat sequences with high GC content and complicated structure. Based on the sequences of human ribosomal DNA repeat unit and transcription unit and the long and accurate PCR method with LA ...
D. Tang, H. Jiang, Y. Zhang, Y. LI, X. Zhang, T. Zhou   +5 more
doaj   +1 more source

RIBOSOMAL DNA IN A NUCLEAR SATELLITE OF TOMATO [PDF]

Genetics, 1975
ABSTRACT A satellite DNA of buoyant density 1.704 constitutes approximately 5%–6% of nuclear DNA isolated from cherry tomato leaves. Isolated satellite DNA exhibits a multi-component melting profile. Kinetic complexity measurements indicate that 37% of the satellite consists of repeating units of 105 daltons, and 48% of it consists of ...
openaire   +2 more sources

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

ABH2 Couples Regulation of Ribosomal DNA Transcription with DNA Alkylation Repair

Cell Reports, 2013
Transcription has been linked to DNA damage. How the most highly transcribed mammalian ribosomal (rDNA) genes maintain genome integrity in the absence of transcription-coupled DNA damage repair is poorly understood.
Pishun Li, Shuman Gao, Lina Wang, Fang Yu, Jialun Li, Chuangui Wang, Jiwen Li, Jiemin Wong   +7 more
doaj   +1 more source

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

Advanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro, Anna Beekmayer‐Dhillon, Qi Wen Teo, Lewis Siu, Ming Yuan Li, Kate J. Heesom, Adán Pinto‐Fernández, Sumana Sanyal   +7 more
wiley   +1 more source

Neurodegeneration-associated instability of ribosomal DNA

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2014
Homologous recombination (HR)-mediated instability of the repetitively organized ribosomal DNA (rDNA) has been proposed as a mediator of cell senescence in yeast triggering the DNA damage response. High individual variability in the content of human rDNA suggests that this genomic region remained relatively unstable throughout evolution.
Hallgren, Justin, Pietrzak, Maciej, Rempala, Grzegorz, Nelson, Peter T., Hetman, Michal   +4 more
openaire   +2 more sources

Fine‐Tuned Regulation of mRNA Translation and Transport by STAU2 Condensate Facilitates Neuronal Development and Plasticity

Advanced Science, EarlyView.
STAU2 undergoes phase separation to form dynamic condensates that package target mRNAs and deliver them to the distal ends of growing neuronal dendrites. STAU2 condensates stabilize embedded mRNAs and repress their translation. Synaptic activity bidirectionally remodels STAU2 condensates, coordinating local translation of STAU2‐associated mRNAs ...
Shijing Huang, Yuanyuan Chu, Ruiqian Zhao, Siyu Li, Yu Feng, Hongdan Zheng, Yunli Xie, Tong Wang, Wenyu Wen   +8 more
wiley   +1 more source

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

Advanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu, Shiming Zhu, Sishi Xia, Xiaoshuai Zhang, Qin Li, Zhanquan Zeng, Yuqing Liu, Wanyin Liang, Guanyu Zhou, Erxia Du, Suning Liu, Sheng Li   +11 more
wiley   +1 more source

Morphological and molecular characterization of Iotonchus lotilabiatus n. sp. (Nematoda: Iotonchidae) from Lao Cai Province, Vietnam [PDF]

Journal of Nematology, 2021
Tam T. T. Vu, Thi Mai Linh Le, Thi Duyen Nguyen   +2 more
doaj   +1 more source

Molecular systematics of the Phyllachorales (ascomycota, fungi) based on 18S ribosomal DNA sequences

Brazilian Archives of Biology and Technology, 2003
In order to evaluate the monophyly of the Phyllachorales from a molecular standpoint and elucidate its phylogenetic relationships with other orders, a segment of the 18S rRNA gene from several representatives of the Phyllachorales, including species of ...
Denise Wanderlei-Silva, Eduardo Ramalho Neto, Richard Hanlin   +2 more
doaj   +1 more source