Results 21 to 30 of about 338,742 (309)

Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation

open access: yesNature Communications, 2020
DNA double-strand breaks in ribosomal DNA repeats is associated with repression of ribosomal RNA synthesis. Here the authors reveal a cooperation between TOPBP1 and Treacle in the signaling cascade that triggers transcriptional inhibition and nucleolar ...
Clémence Mooser   +15 more
doaj   +1 more source

Characterization of Pratylenchus crenatus and P. neglectus (Nematoda: Pratylenchidae) associated with wheat crop

open access: yesHelminthologia, 2015
The distribution of Pratylenchus species associated with wheat crops was investigated in Bohemian region of the Czech Republic. In total twelve localities were sampled.
Kumari S.
doaj   +1 more source

Cic1p/Nsa3p is required for synthesis and nuclear export of 60S ribosomal subunits [PDF]

open access: yes, 2003
Cic1p/Nsa3p was previously reported to be associated with the 26S proteasome and required for the degradation of specific substrates, but was also shown to be associated with early pre-60S particles and to be localized to the nucleolus.
Tollervey, D   +7 more
core   +1 more source

Phylogenetic studies on three Helicotylenchus species based on 28S rDNA and mtCOI sequence data

open access: yesJournal of Nematology, 2019
To facilitate the process of spiral nematode species delineation, populations of Helicotylenchus canadensis, H. pseudorobustus, and H. varicaudatus deriving from various locations and diverse natural and anthropogenic environments from Poland were ...
Rybarczyk-Mydłowska K.   +2 more
doaj   +1 more source

SMN-deficient cells exhibit increased ribosomal DNA damage

open access: yesLife Science Alliance, 2022
SMN deficiency leads to elevated ribosomal DNA damage that results in impaired ribosomal RNA synthesis and translation and is accompanied by a motor neuron-specific down-regulation of DDX21 protein.
Evangelia Karyka   +13 more
doaj   +1 more source

Similarity between the association factor of ribosomal subunits and the protein Stm1p from Saccharomyces cerevisiae

open access: yesMemorias do Instituto Oswaldo Cruz, 2004
A ribosome association factor (AF) was isolated from the yeast Sacchharomyces cerevisiae. Partial amino acid sequence of AF was determined from its fragment of 25 kDa isolated by treating AF with 2-(2-nitrophenylsulfenyl)-3-methyl-3'-Bromoindolenine ...
Heriberto Correia   +5 more
doaj   +1 more source

The DNA helicase Pfh1 promotes fork merging at replication termination sites to ensure genome stability [PDF]

open access: yes, 2012
Bidirectionally moving DNA replication forks merge at termination sites composed of accidental or programmed DNA-protein barriers. If merging fails, then regions of unreplicated DNA can result in the breakage of DNA during mitosis, which in turn can give
Steinacher, R.   +14 more
core   +1 more source

Function of the upstream activating factor in chromatin structure organization and transcriptional regulation at the yeast ribosomal DNA

open access: yes, 2010
Chromatin is the template of all processes involved in DNA metabolism in the eukaryotic cell. Accordingly, chromatin is a dynamic structure which changes in its composition and posttranslational modification correlating with the functional state of a ...
Götze, Hannah
core   +1 more source

PCR amplification of a long rDNA segment with one primer pair in agriculturally important nematodes

open access: yesJournal of Nematology, 2019
Ribosomal DNA has been a reliable source of taxonomic and phylogenetic markers due to its high copy number in the genome and stable variation with few polymorphisms due to the homogenizing effect of concerted evolution.
Carta L. K., Li S.
doaj   +1 more source

DNA Methylation Analysis of Ribosomal DNA in Adults With Down Syndrome

open access: yesFrontiers in Genetics, 2022
Control of ribosome biogenesis is a critical aspect of the regulation of cell metabolism. As ribosomal genes (rDNA) are organized in repeated clusters on chromosomes 13, 14, 15, 21, and 22, trisomy of chromosome 21 confers an excess of rDNA copies to ...
Francesco Ravaioli   +26 more
doaj   +1 more source

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