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Chromatin states at ribosomal DNA loci

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2013
Eukaryotic transcription of ribosomal RNAs (rRNAs) by RNA polymerase I can account for more than half of the total cellular transcripts depending on organism and growth condition. To support this level of expression, eukaryotic rRNA genes are present in multiple copies.
Stephan, Hamperl   +5 more
openaire   +2 more sources

Ribosomal DNA in Maize

1988
The nucleolus organizer region (NOR) of maize chromosome 6 is now known to be the location of the 17/5.8/26S rDNA (hereafter termed 17/26S rDNA); this molecular information extends the NOR function to one of synthesizer as well as organizer. The extensive variation in ribosomal DNA (rDNA) multiplicity and the finding that much of the rDNA is in the NOR-
R. L. Phillips   +3 more
openaire   +1 more source

Replicon size of yeast ribosomal DNA

Molecular and General Genetics MGG, 1984
The ribosomal RNAs of the yeast Saccharomyces cerevisiae are transcribed from a 9K bp stretch of DNA which is reiterated about 120-fold in a continuous array, about 360 microns long, on chromosome XII. Although ARS activity has been detected in the repeat unit, the size and disposition of replicons along this array of identical genes has not hitherto ...
Walmsley, Richard M.   +3 more
openaire   +3 more sources

The ribosomal DNA of Calliphora erythrocephala; an analysis of hybrid plasmids containing ribosomal DNA

Journal of Molecular Biology, 1980
Abstract We have analysed the ribosomal DNA of Calliphora erythrocephala, a Dipteran fly of the same sub-order as Drosophila melanogaster, through a series of rDNA † fragments cloned in a plasmid vector. We have mapped the sites for eight restriction enzymes within these plasmids, and positioned the regions coding for the 18 S and 28 S rRNAs within ...
K, Beckingham, R, White
openaire   +2 more sources

Ribosome cycle emerges from DNA replication

Nature Reviews Molecular Cell Biology, 2017
A modification of Meselson and Stahl's density gradient centrifugation method and a rare Texan yeast helped show that eukaryotic ribosomes dissociate and reform during translation.
openaire   +2 more sources

The evolution of eukaryotic ribosomal DNA

Biosystems, 1986
Mutations occur randomly throughout the ribosomal DNA (rDNA) sequence. Molecular drive (unequal crossing-over, gene conversion, and transposition) spreads these variations through the multiple copies of rDNA. Forces of selection act upon the variants to favor and fix them or disfavor and eliminate them.
openaire   +2 more sources

Heterogeneity in Chinese hamster ribosomal DNA

Chromosoma, 1978
A discrete heterogeneity has been detected in Chinese hamster ribosomal DNA after Eco R1 digestion of total DNA followed by a Southern transfer and hybridization with [125I]18S or [125I]28S ribosomal RNA. Digestion with Eco R1 produces three fragments, 4.3, 6.0 and 9.5 x 10(6) daltons respectively, which hybridize with 18S RNA.
openaire   +2 more sources

Regulation of ribosomal RNA gene copy number, transcription and nucleolus organization in eukaryotes

Nature reviews. Molecular cell biology, 2023
Yutaro Hori   +2 more
semanticscholar   +1 more source

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