Results 151 to 160 of about 874,984 (309)
Crowding induces entropically-driven changes to DNA dynamics that depend on crowder structure and ionic conditions [PDF]
arXiv, 2018 Macromolecular crowding plays a principal role in a wide range of biological processes including gene expression, chromosomal compaction, and viral infection. However, the impact that crowding has on the dynamics of nucleic acids remains a topic of debate.
arxiv
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
Metagenomic Assessment of DNA Viral Diversity in Freshwater Sponges, Baikalospongia bacillifera. [PDF]
Microorganisms, 2022 Butina TV +3 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.Integrating selective RNA shortcut, targeted gene isolation, and micro‐arrayed nanoimaging, the NanoPick‐array platform excels in detecting severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) at just 60 copies µL−1 and accurately differentiating variants at the single‐nucleotide level. It ensures 100% accuracy for samples with cycle threshold (
Zixun Wang +9 more
wiley +1 more source
Longitudinal Monitoring of DNA Viral Loads in Transplant Patients Using Quantitative Metagenomic Next-Generation Sequencing. [PDF]
Pathogens, 2022 Carbo EC +8 more
europepmc +1 more source
Identification of a Proliferation Gene Cluster Associated with HPV E6/E7 Expression Level and Viral DNA Load in Invasive Cervical Carcinoma [PDF]
Oncogene vol 24, p 7094-7104 (2005), 2005 Specific HPV DNA sequences are associated with more than 90% of invasive carcinomas of the uterine cervix. Viral E6 and E7 oncogenes are key mediators in cell transformation by disrupting TP53 and RB pathways. To investigate molecular mechanisms involved in the progression of invasive cervical carcinoma, we performed a gene expression study on cases ...
arxiv
Nanozymes for Treating Ocular Diseases
Advanced Healthcare Materials, EarlyView.Nanozymes, with their nanoscale size and enzyme‐like activities, can reduce inflammation and oxidative stress associated with various ocular diseases. Recent research explores their integration with soft materials, nanoparticles, and drug delivery systems, promising enhanced therapeutic outcomes.
Ka‐Ying Wong +2 more
wiley +1 more source
DNA Viral Diversity, Abundance, and Functional Potential Vary across Grassland Soils with a Range of Historical Moisture Regimes. [PDF]
mBio, 2021 Wu R +10 more
europepmc +1 more source
mBioThe integration of HPV DNA into human chromosomes plays a pivotal role in the onset of papillomavirus-related cancers. HPV DNA integration often occurs by linearizing the viral DNA in the E1/E2 region, resulting in the loss of a critical viral early ...
Lulu Yu +9 more
doaj +1 more source
Iron‐MOFs for Biomedical Applications
Advanced Healthcare Materials, EarlyView.This review introduces the unique properties of iron‐based metal–organic frameworks (Fe‐MOFs), the advances in synthesis and formulation, and their state‐of‐the‐art applications in biomedicine. It discusses the challenges in transitioning Fe‐MOFs from research to clinical use, emphasizing the need for eco‐friendly production methods, and a deeper ...
Zhihao Yu +2 more
wiley +1 more source