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DNA Probes for Viral Diagnosis
1992Great excitement has surrounded the development of molecular hybridization techniques for viruses because of the potential of nucleic acid probes as diagnostic reagents. The need for rapid and accurate viral diagnosis has become particularly pressing with the recent availability of numerous drugs which have been clinically proven as effective in ...
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2001
Update on antiviral DNA vaccine research (1998-2000) optimization strategies for DNA vaccines relative potency of cellular and humoral immune responses induced by DNA vaccination improving DNA vaccines targeting viral infection alphavirus vectors - applications for DNA vaccine production and gene expression plasmid DNA vaccines - investigation of ...
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Update on antiviral DNA vaccine research (1998-2000) optimization strategies for DNA vaccines relative potency of cellular and humoral immune responses induced by DNA vaccination improving DNA vaccines targeting viral infection alphavirus vectors - applications for DNA vaccine production and gene expression plasmid DNA vaccines - investigation of ...
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An Error-Prone Viral DNA Ligase
Biochemistry, 2005Our recent demonstration that DNA polymerase X (Pol X), the DNA repair polymerase encoded by the African swine fever virus (ASFV), is extremely error prone during single-nucleotide gap filling led us to hypothesize that it might contribute to genetic variability in ASFV.
and Alexander K. Showalter +2 more
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Virology, 1977
Abstract The amount of viral DNA present in a viral transformed cell line has been determined using saturation reassociation of cellular DNA and 125 I-labeled viral DNA. The virus, RFV, is a new human papovavirus which was used to transform hamster embryo cells in vitro .
R.M. Dougherty, R. Miao
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Abstract The amount of viral DNA present in a viral transformed cell line has been determined using saturation reassociation of cellular DNA and 125 I-labeled viral DNA. The virus, RFV, is a new human papovavirus which was used to transform hamster embryo cells in vitro .
R.M. Dougherty, R. Miao
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Packaging of DNA origami in viral capsids
Nanoscale, 2019DNA origami in self-assembled SV40 capsid, a new type of encapsulation substrate for medical applications.
Idit Kopatz +5 more
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2014
Adenoviren verursachen im Kindesalter Krankheiten der Atemwege und des Darms, aber auch Krankheiten der Harnwege, der Lymphorgane, kardiologische und neurologische Manifestationen werden beobachtet. Einige typische Krankheitsbilder konnen klinisch diagnostiziert werden.
Volker Schuster +2 more
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Adenoviren verursachen im Kindesalter Krankheiten der Atemwege und des Darms, aber auch Krankheiten der Harnwege, der Lymphorgane, kardiologische und neurologische Manifestationen werden beobachtet. Einige typische Krankheitsbilder konnen klinisch diagnostiziert werden.
Volker Schuster +2 more
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A nuclear sensor of viral DNA?
Science, 2019Immune Signaling A signaling pathway in eukaryotes known as cGAS–STING recognizes the presence of cytosolic DNA, which alerts the immune system to viral infection or cellular damage. However, the majority of DNA viruses direct their genomic DNA into nuclei, suggesting that nuclear-specific sensing is also needed. L. Wang et al.
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Conformational Properties of Some Viral DNAs
European Journal of Biochemistry, 1974Oriented films of bacteriophage DNAs of low and intermediate (G + C) content and of different chemical composition were investigated by infrared linear dichroism: PBS1, DNA (28% G + C, uracil replaces thymine), T4, DNA (34%, G + C, glucosylated), T4* DNA (34% G + C, unglucosylated), T5, DNA (39% G + C).
P. Champell, J. Brahms
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Mechanochemistry of a Viral DNA Packaging Motor
Journal of Molecular Biology, 2010The pentameric ATPase motor gp16 packages double-stranded DNA into the bacteriophage phi29 virus capsid. On the basis of the results of single-molecule experimental studies, we propose a push and roll mechanism to explain how the packaging motor translocates the DNA in bursts of four 2.5 bp power strokes, while rotating the DNA. In this mechanism, each
Jeffrey R. Moffitt +4 more
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1983
Publisher Summary The small size and relative homogeneity of viral DNA facilitates its isolation and the detailed characterization of its physical and genetic properties. As the virus and/or its nucleic acid genome can usually be purified to homogeneity, it is possible to eliminate or control indirect effects in the course of treatment. The viral DNA
Martine Defais +2 more
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Publisher Summary The small size and relative homogeneity of viral DNA facilitates its isolation and the detailed characterization of its physical and genetic properties. As the virus and/or its nucleic acid genome can usually be purified to homogeneity, it is possible to eliminate or control indirect effects in the course of treatment. The viral DNA
Martine Defais +2 more
openaire +2 more sources