Results 231 to 240 of about 947,078 (263)

Safety of Viral DNA in Biological Products

Biologicals, 1998
Data from studies of the infectivity of DNA injected directly into laboratory animals are used to estimate the potential infectivity risk of residual DNA in biological products. The potential for some novel products to contain infectious quantities of residual cellular DNA is discussed, and further study of this subject is suggested.
Philip R. Krause, Andrew M. Lewis
openaire   +3 more sources

Organization of type C viral DNA sequences endogenous to baboons: analysis with cloned viral DNA

Journal of Virology, 1982
Unintegrated linear and circular forms of baboon endogenous type C virus M7 DNA were prepared from M7-infected cells by chromatography on hydroxyapatite columns, and the circular DNAs were purified in cesium chloride-ethidium bromide equilibrium density gradients. The circular DNAs were linearized by digestion with EcoRI, which had a unique site on the
N Battula, G L Hager, G J Todaro
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Branched DNA for Quantification of Viral LOAD

Immunological Investigations, 1997
This is a summary of a presentation made at the 13th International Convocation on Immunology. Nucleic acids in patient samples can be quantified directly using a solid phase nucleic acid hybridization assay based on branched DNA (bDNA) signal amplification technology.
openaire   +3 more sources

Viral Vaccines and Residual Cellular DNA

Biologicals, 1995
The acceptability of viral vaccines manufactured in culture of continuous cell lines opened the way to a new technology of vaccine preparation. The large scale cultivation of continuous cell lines contributed greatly to the improvement of the safety and the consistency of viral vaccines.
openaire   +2 more sources

Evolution of viral DNA-dependent DNA polymerases.

Virus genes, 1998
DNA viruses as their host cells require a DNA-dependent DNA polymerase (Pol) to faithfully replicate their genomic information. Large eukaryotic DNA viruses as well as bacterial viruses encode a specific Pol equipped with a proofreading 3'-5'-exonuclease, and other replication proteins. All known viral Pol belong to family A and family B Pol. Common to
openaire   +3 more sources

Integration of Viral DNA into the Host Genome

1975
Animal viruses can interact with their host cells in different ways: (1) The virus can actively replicate and finally destroy the cell in a lytic or productive infection. (2) The infection can become abortive or non-productive and lead to the apparent or inapparent persistence or the eventual loss of the viral genome.
openaire   +3 more sources

The Anatomy of Viral DNA Molecules

Annual Review of Biochemistry, 1967
L A MacHattie, C A Thomas
openaire   +3 more sources

DNA Sequencing of Viral Genomes

1979
In his book Biochemistry Lehninger (1970) illustrated the complexity of the genetic material by devoting a full page to closely spaced arrays of A, G, C, and T letters, calling this “an imaginary base sequence for the chromosome of bacteriophage oX174” and pointing out that this is one of the smallest DNA genomes known.
openaire   +2 more sources

Cardio‐oncology care in the era of the coronavirus disease 2019 (COVID‐19) pandemic: An International Cardio‐Oncology Society (ICOS) statement

Ca-A Cancer Journal for Clinicians, 2020
Daniel J Lenihan, Joseph Carver, Charles Porter   +2 more
exaly  

Viral and host heterogeneity and their effects on the viral life cycle

Nature Reviews Microbiology, 2021
Jennifer E Jones, Valerie Le Sage, Seema S Lakdawala   +2 more
exaly