Results 271 to 280 of about 1,132,058 (308)

Safety of Viral DNA in Biological Products

Biologicals, 1998
Data from studies of the infectivity of DNA injected directly into laboratory animals are used to estimate the potential infectivity risk of residual DNA in biological products. The potential for some novel products to contain infectious quantities of residual cellular DNA is discussed, and further study of this subject is suggested.
P R, Krause, A M, Lewis
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Characterization of human papovavirus RFV: Use of iodinated viral DNA to detect viral DNA sequences in cellular DNA

Virology, 1977
Abstract The amount of viral DNA present in a viral transformed cell line has been determined using saturation reassociation of cellular DNA and 125 I-labeled viral DNA. The virus, RFV, is a new human papovavirus which was used to transform hamster embryo cells in vitro .
R, Miao, R M, Dougherty
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Organization of type C viral DNA sequences endogenous to baboons: analysis with cloned viral DNA

Journal of Virology, 1982
Unintegrated linear and circular forms of baboon endogenous type C virus M7 DNA were prepared from M7-infected cells by chromatography on hydroxyapatite columns, and the circular DNAs were purified in cesium chloride-ethidium bromide equilibrium density gradients. The circular DNAs were linearized by digestion with EcoRI, which had a unique site on the
N, Battula, G L, Hager, G J, Todaro
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Viral DNA Vaccines

2001
Update on antiviral DNA vaccine research (1998-2000) optimization strategies for DNA vaccines relative potency of cellular and humoral immune responses induced by DNA vaccination improving DNA vaccines targeting viral infection alphavirus vectors - applications for DNA vaccine production and gene expression plasmid DNA vaccines - investigation of ...
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Viral Vaccines and Residual Cellular DNA

Biologicals, 1995
The acceptability of viral vaccines manufactured in culture of continuous cell lines opened the way to a new technology of vaccine preparation. The large scale cultivation of continuous cell lines contributed greatly to the improvement of the safety and the consistency of viral vaccines.
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Branched DNA for Quantification of Viral LOAD

Immunological Investigations, 1997
This is a summary of a presentation made at the 13th International Convocation on Immunology. Nucleic acids in patient samples can be quantified directly using a solid phase nucleic acid hybridization assay based on branched DNA (bDNA) signal amplification technology.
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Integration of Viral DNA into the Host Genome

1975
Animal viruses can interact with their host cells in different ways: (1) The virus can actively replicate and finally destroy the cell in a lytic or productive infection. (2) The infection can become abortive or non-productive and lead to the apparent or inapparent persistence or the eventual loss of the viral genome.
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Virale Infektionen: DNA-Viren

2014
Adenoviren verursachen im Kindesalter Krankheiten der Atemwege und des Darms, aber auch Krankheiten der Harnwege, der Lymphorgane, kardiologische und neurologische Manifestationen werden beobachtet. Einige typische Krankheitsbilder konnen klinisch diagnostiziert werden.
Johannes Forster, Volker Schuster, Hans Wolfgang Kreth   +2 more
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A nuclear sensor of viral DNA?

Science, 2019
Immune Signaling A signaling pathway in eukaryotes known as cGAS–STING recognizes the presence of cytosolic DNA, which alerts the immune system to viral infection or cellular damage. However, the majority of DNA viruses direct their genomic DNA into nuclei, suggesting that nuclear-specific sensing is also needed. L. Wang et al.
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The Anatomy of Viral DNA Molecules

Annual Review of Biochemistry, 1967
C A, Thomas, L A, MacHattie
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