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An Error-Prone Viral DNA Ligase
Biochemistry, 2005Our recent demonstration that DNA polymerase X (Pol X), the DNA repair polymerase encoded by the African swine fever virus (ASFV), is extremely error prone during single-nucleotide gap filling led us to hypothesize that it might contribute to genetic variability in ASFV.
Brandon J, Lamarche +2 more
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Production of Non Viral DNA Vectors
Current Gene Therapy, 2010After some decades of research, development and first clinical approaches to use DNA vectors in gene therapy, cell therapy and DNA vaccination, the requirements for the pharmaceutical manufacturing of gene vectors has improved significantly step by step.
Martin, Schleef +6 more
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2001
Update on antiviral DNA vaccine research (1998-2000) optimization strategies for DNA vaccines relative potency of cellular and humoral immune responses induced by DNA vaccination improving DNA vaccines targeting viral infection alphavirus vectors - applications for DNA vaccine production and gene expression plasmid DNA vaccines - investigation of ...
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Update on antiviral DNA vaccine research (1998-2000) optimization strategies for DNA vaccines relative potency of cellular and humoral immune responses induced by DNA vaccination improving DNA vaccines targeting viral infection alphavirus vectors - applications for DNA vaccine production and gene expression plasmid DNA vaccines - investigation of ...
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2014
Adenoviren verursachen im Kindesalter Krankheiten der Atemwege und des Darms, aber auch Krankheiten der Harnwege, der Lymphorgane, kardiologische und neurologische Manifestationen werden beobachtet. Einige typische Krankheitsbilder konnen klinisch diagnostiziert werden.
Johannes Forster +2 more
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Adenoviren verursachen im Kindesalter Krankheiten der Atemwege und des Darms, aber auch Krankheiten der Harnwege, der Lymphorgane, kardiologische und neurologische Manifestationen werden beobachtet. Einige typische Krankheitsbilder konnen klinisch diagnostiziert werden.
Johannes Forster +2 more
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Conformational Properties of Some Viral DNAs
European Journal of Biochemistry, 1974Oriented films of bacteriophage DNAs of low and intermediate (G + C) content and of different chemical composition were investigated by infrared linear dichroism: PBS1, DNA (28% G + C, uracil replaces thymine), T4, DNA (34%, G + C, glucosylated), T4* DNA (34% G + C, unglucosylated), T5, DNA (39% G + C).
P, Champeil, J, Brahms
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DNA Probes for Viral Diagnosis
1992Great excitement has surrounded the development of molecular hybridization techniques for viruses because of the potential of nucleic acid probes as diagnostic reagents. The need for rapid and accurate viral diagnosis has become particularly pressing with the recent availability of numerous drugs which have been clinically proven as effective in ...
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Serum Hepatitis B Viral DNA in Acute Viral Hepatitis B
Annals of Internal Medicine, 1989Excerpt There is no way to identify which patients with acute hepatitis B infection will recover and which will become chronic carriers.
T L, Fong +4 more
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Quantitation of bovine papilloma viral DNA in viral-induced tumors
Journal of Virology, 1976Bovine papilloma virus (BPV) DNA was labeled in vitro under conditions of repair synthesis and subsequently used as a "probe" in DNA-DNA reassociation studies to detect BPV-specific DNA sequences in a viral-induced calf meningioma and hamster fibroma.
W D, Lancaster, C, Olson, W, Meinke
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Vaccinia DNA: Separation of viral from host cell DNA
Archiv f�r die gesamte Virusforschung, 1967Virus and cell DNA were separated by isopycnic centrifugation after subjecting a mixture to denaturation and reannealing. Virus DNA renatured, while cell DNA retained the density of single-stranded material. This process magnified the originally very small density difference between the two DNA's.
C, Jungwirth, I B, Dawid
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Viral Vaccines and Residual Cellular DNA
Biologicals, 1995The acceptability of viral vaccines manufactured in culture of continuous cell lines opened the way to a new technology of vaccine preparation. The large scale cultivation of continuous cell lines contributed greatly to the improvement of the safety and the consistency of viral vaccines.
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