Results 301 to 310 of about 3,750,929 (346)

Characterization of human papovavirus RFV: Use of iodinated viral DNA to detect viral DNA sequences in cellular DNA

Virology, 1977
Abstract The amount of viral DNA present in a viral transformed cell line has been determined using saturation reassociation of cellular DNA and 125 I-labeled viral DNA. The virus, RFV, is a new human papovavirus which was used to transform hamster embryo cells in vitro .
R.M. Dougherty, R. Miao
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A nuclear sensor of viral DNA?

Science, 2019
Immune Signaling A signaling pathway in eukaryotes known as cGAS–STING recognizes the presence of cytosolic DNA, which alerts the immune system to viral infection or cellular damage. However, the majority of DNA viruses direct their genomic DNA into nuclei, suggesting that nuclear-specific sensing is also needed. L. Wang et al.
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Conformational Properties of Some Viral DNAs

European Journal of Biochemistry, 1974
Oriented films of bacteriophage DNAs of low and intermediate (G + C) content and of different chemical composition were investigated by infrared linear dichroism: PBS1, DNA (28% G + C, uracil replaces thymine), T4, DNA (34%, G + C, glucosylated), T4* DNA (34% G + C, unglucosylated), T5, DNA (39% G + C).
P. Champell, J. Brahms
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Virale Infektionen: DNA-Viren

2014
Adenoviren verursachen im Kindesalter Krankheiten der Atemwege und des Darms, aber auch Krankheiten der Harnwege, der Lymphorgane, kardiologische und neurologische Manifestationen werden beobachtet. Einige typische Krankheitsbilder konnen klinisch diagnostiziert werden.
Volker Schuster, Johannes Forster, Hans Wolfgang Kreth   +2 more
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Mechanochemistry of a Viral DNA Packaging Motor

Journal of Molecular Biology, 2010
The pentameric ATPase motor gp16 packages double-stranded DNA into the bacteriophage phi29 virus capsid. On the basis of the results of single-molecule experimental studies, we propose a push and roll mechanism to explain how the packaging motor translocates the DNA in bursts of four 2.5 bp power strokes, while rotating the DNA. In this mechanism, each
Jeffrey R. Moffitt, Jin Yu, Craig L. Hetherington, Carlos Bustamante, George Oster   +4 more
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Safety of Viral DNA in Biological Products

Biologicals, 1998
Data from studies of the infectivity of DNA injected directly into laboratory animals are used to estimate the potential infectivity risk of residual DNA in biological products. The potential for some novel products to contain infectious quantities of residual cellular DNA is discussed, and further study of this subject is suggested.
Philip R. Krause, Andrew M. Lewis
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Viral Probes for DNA Repair

1983
Publisher Summary The small size and relative homogeneity of viral DNA facilitates its isolation and the detailed characterization of its physical and genetic properties. As the virus and/or its nucleic acid genome can usually be purified to homogeneity, it is possible to eliminate or control indirect effects in the course of treatment. The viral DNA
Martine Defais, Alain Sarasin, Philip C. Hanawalt   +2 more
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Organization of type C viral DNA sequences endogenous to baboons: analysis with cloned viral DNA

Journal of Virology, 1982
Unintegrated linear and circular forms of baboon endogenous type C virus M7 DNA were prepared from M7-infected cells by chromatography on hydroxyapatite columns, and the circular DNAs were purified in cesium chloride-ethidium bromide equilibrium density gradients. The circular DNAs were linearized by digestion with EcoRI, which had a unique site on the
N Battula, G L Hager, G J Todaro
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Branched DNA for Quantification of Viral LOAD

Immunological Investigations, 1997
This is a summary of a presentation made at the 13th International Convocation on Immunology. Nucleic acids in patient samples can be quantified directly using a solid phase nucleic acid hybridization assay based on branched DNA (bDNA) signal amplification technology.
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Viral Vaccines and Residual Cellular DNA

Biologicals, 1995
The acceptability of viral vaccines manufactured in culture of continuous cell lines opened the way to a new technology of vaccine preparation. The large scale cultivation of continuous cell lines contributed greatly to the improvement of the safety and the consistency of viral vaccines.
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