Results 101 to 110 of about 1,065,519 (331)
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef+10 more
wiley +1 more source
The genus Trichoderma is a soil-borne fungi which in numerous reports has been successfully used as a biological control agent against various plant pathogens.
Shafiquzzaman Siddiquee+4 more
doaj +1 more source
Recognition of Ribosomal RNA Sites in DNA, I. Analysis of the E. coli System [PDF]
The evidence recently presented of specific hybridization between bacterial ribosomal RNA and homologous DNA1-3 has indicated the possibility of a biochemical approach to the problem of the identification of ribosomal RNA sites in DNA.
Attardi, Giuseppe+2 more
core +1 more source
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková+14 more
wiley +1 more source
A cellulose-based bioassay for the colorimetric detection of pathogen DNA [PDF]
Cellulose-paper-based colorimetric bioassays may be used at the point of sampling without sophisticated equipment. This study reports the development of a colorimetric bioassay based on cellulose that can detect pathogen DNA.
Goyal, Madhu+3 more
core +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
An Electrochemical DNA Microbiosensor Based on Succinimide-Modified Acrylic Microspheres
An electrochemical microbiosensor for DNA has been fabricated based on new acrylic microspheres modified with reactive <em>N</em>-acryloxysuccinimide (NAS) functional groups.
Sharina Abu Hanifah+3 more
doaj +1 more source
Bismuth oxide nanoparticles/chitosan/modified electrode as biosensor for DNA hybridization. [PDF]
An electrochemical DNA biosensor based on nanoparticles bismuth oxide Bi2O3 for DNA immobilization and hybridization detection is presented. The nano Bi2O3/chitosan-modified gold electrode (AuE) was fabricated and oligonucleotides were immobilized onto ...
Ramli, Irmawati+3 more
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