Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila+7 more
wiley +1 more source
Germ Line-Specific DNA Sequences are Present on All Five Micronuclear Chromosomes in \u3cem\u3eTetrahymena thermophila\u3c/em\u3e [PDF]
The development of the macronucleus from the zygotic micronucleus in the ciliated protozoan Tetrahymena spp. involves the elimination of specific DNA sequences (M. C. Yao and M. Gorovsky, Chromosoma 48:1-18 1974).
Karrer, Kathleen M.
core +1 more source
Use of Nucleic Acid Hybridization for Specific Detection of Submicrogram Quantities of DNA, and Its Application to Human Plasma [PDF]
Charles R. Steinman
openalex +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source
MOLECULAR HYBRIDIZATION OF RADIOACTIVE DNA TO THE DNA OF CYTOLOGICAL PREPARATIONS
Mary Lou Pardue, Joseph G. Gall
openalex +1 more source
Origins of phage T4 DNA replication as revealed by hybridization to cloned genes. [PDF]
Marnie E. Halpern+2 more
openalex +1 more source
A sequence‐encoded supramolecular construct containing two accessible toeholds is developed herein for enabling multiple editing operations. By introducing specific input strands, it is possible to selectively erase or rewrite digital content through parallel or series toehold‐mediated strand displacement (PTMSD or STMSD).
Jakub Ossowski+3 more
wiley +1 more source
The chemical synthesis of deoxyribo‐oligonucleotides complementary to a portion of the lysozyme gene of phage T4 and their hybridization to phage specific RNA and phage DNA [PDF]
M.T. Doel, Michael J. Smith
openalex +1 more source
Epitaxial piezoelectric α‐quartz/Si BioNEMS sensors, made using soft chemistry, effectively detect the Chikungunya virus. They have a mass sensitivity of 205 pg Hz−1 in liquid and can detect the virus at a limit of 9 ng mL−1. This development enables high‐frequency mass devices for point‐of‐care testing in healthcare and other electronic applications ...
Raissa Rathar+12 more
wiley +1 more source
Hybridization of labeled RNA to DNA in agarose gels [PDF]
Thomas M. Shinnick+3 more
openalex +1 more source