Results 11 to 20 of about 657,941 (288)

Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries [PDF]

open access: yes, 1988
A method of in situ hybridization for visualizing individual human chromosomes from pter to qter, both in metaphase spreads and interphase nuclei, is reported.
B Trask   +39 more
core   +1 more source

The Implications of Fragmented Genomic DNA Size Range on the Hybridization Efficiency in NanoGene Assay

open access: yesSensors, 2018
DNA hybridization-based assays are well known for their ability to detect and quantify specific bacteria. Assays that employ DNA hybridization include a NanoGene assay, fluorescence in situ hybridization, and microarrays.
Xiaofang Wang, Beelee Chua, Ahjeong Son
doaj   +1 more source

Compressive Sensing DNA Microarrays [PDF]

open access: yes, 2008
Compressive sensing microarrays (CSMs) are DNA-based sensors that operate using group testing and compressive sensing (CS) principles. In contrast to conventional DNA microarrays, in which each genetic sensor is designed to respond to a single target, in
Baraniuk, RG   +3 more
core   +1 more source

Thermodynamic analysis of DNA hybridization signatures near mitochondrial DNA deletion breakpoints

open access: yesiScience, 2021
Summary: Broad evidence in the literature supports double-strand breaks (DSBs) as initiators of mitochondrial DNA (mtDNA) deletion mutations. While DNA misalignment during DSB repair is commonly proposed as the mechanism by which DSBs cause deletion ...
Lakshmi Narayanan Lakshmanan   +4 more
doaj   +1 more source

Studies on Nucleic Acid Reassociation Kinetics: Retarded Rate of Hybridization of RNA with Excess DNA [PDF]

open access: yes, 1977
The rate of reaction of excess double-stranded bacteriophage phi X174 and plasmid RSF2124 DNA drivers with enzymatically synthesized asymmetric RNA tracers was measured. Other reactions were carried out with excess Escherichia coli DNA and E.
Britten, Roy J.   +3 more
core   +1 more source

Hybridization and self‐assembly behaviors of surface‐immobilized DNA in close proximity: A single‐molecule perspective

open access: yesAggregate, 2022
Solid surfaces that are immobilized with DNA molecules underlie an array of biotechnological devices. These surfaces may also mediate the self‐assembly of hierarchical DNA nanostructures.
Qufei Gu, Eric A. Josephs, Tao Ye
doaj   +1 more source

Rapid generation of chromosome-specific alphoid DNA probes using the polymerase chain reaction [PDF]

open access: yes, 1992
Non-isotopic in situ hybridization of chromosome-specific alphoid DNA probes has become a potent tool in the study of numerical aberrations of specific human chromosomes at all stages of the cell cycle. In this paper, we describe approaches for the rapid
A Gnirke   +33 more
core   +1 more source

Use of the checkerboard DNA-DNA hybridization technique for bacteria detection in Aedes aegypti (Diptera:Culicidae) (L.)

open access: yesParasites & Vectors, 2011
Background Bacteria associated with insects can have a substantial impact on the biology and life cycle of their host. The checkerboard DNA-DNA hybridization technique is a semi-quantitative technique that has been previously employed in odontology to ...
Gaio Analiz de Oliveira   +6 more
doaj   +1 more source

Epidemiological Typing of Moraxella Catarrhalis by Pulsed Field Gel Electrophoresis

open access: yesCanadian Journal of Infectious Diseases, 1995
Pulsed field gel electrophoresis (pfge) was used to compare 59 strains of Moraxella catarrhalis to evaluate pfge for the epidemiological typing of this organism.
Susan M Davison   +4 more
doaj   +1 more source

Hybridization Parameters Revisited: Solutions Containing SDS

open access: yesBioTechniques, 2002
Salt concentration governs nucleic acid hybridization according to the Schildkraut-Lifson equation. High concentrations of SDS are used in some common protocols, but the effects of SDS on hybridization stringency have not been reported.
Ken Rose, John O. Mason, Richard Lathe
doaj   +1 more source

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