Results 21 to 30 of about 657,941 (288)

Impact of point-mutations on the hybridization affinity of surface-bound DNA/DNA and RNA/DNA oligonucleotide-duplexes: Comparison of single base mismatches and base bulges

BMC Biotechnology, 2008
Background The high binding specificity of short 10 to 30 mer oligonucleotide probes enables single base mismatch (MM) discrimination and thus provides the basis for genotyping and resequencing microarray applications.
Mai Timo, Kayser Jona, Ehler Oliver, Naiser Thomas, Michel Wolfgang, Ott Albrecht   +5 more
doaj   +1 more source

Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84 [PDF]

, 1986
The localization of chromosome 18 in human interphase nuclei is demonstrated by use of radioactive and nonradioactive in situ hybridization techniques with a DNA clone designated L1.84.
A. Brückner, AHN Hopman, AL Jørgensen, AR Mitchell, B Trask, BU Zabel, CD Bloomfield, D Pinkel, GA Rappold, GA Rappold, H Hoehn, H. D. Hager, H. P. Scholl, HF Willard, J Wolfe, J. Landegent, JC Wu, JE Landegent, JE Landegent, L Manuelidis, LA Herzenberg, M Schardin, M Schmid, M Spaeter, M. Schardin, M. van der Ploeg, MM LeBeau, P Devilee, P Devilee, P. Devilee, P. Pearson, T Cremer, T. Cremer, W Schempp   +33 more
core   +1 more source

Design and analysis of linear cascade DNA hybridization chain reactions using DNA hairpins

New Journal of Physics, 2017
DNA self-assembly has been employed non-conventionally to construct nanoscale structures and dynamic nanoscale machines. The technique of hybridization chain reactions by triggered self-assembly has been shown to form various interesting nanoscale ...
Hieu Bui, Sudhanshu Garg, Vincent Miao, Tianqi Song, Reem Mokhtar, John Reif   +5 more
doaj   +1 more source

Development of Si-based electrical biosensors: Simulations and first experimental results

Sensing and Bio-Sensing Research, 2015
In this work, we simulated and experimentally assessed the possibility to detect, through electrical transduction, hybridization of DNA molecules on MOS-like devices, having different dielectrics: SiO2, Si3N4 and SiO2/Si3N4/SiO2 (ONO).
Marco Favetta, Antonio Valletta, Guglielmo Fortunato, Maria Eloisa Castagna, Sabrina Conoci, Emanuele Luigi Sciuto, Tiziana Cosentino, Fulvia Sinatra, Sebania Libertino   +8 more
doaj   +1 more source

DNA Sensing Platforms: Novel Insights into Molecular Grafting Using Low Perturbative AFM Imaging

Sensors, 2023
By using AFM as a nanografting tool, we grafted micrometer-sized DNA platforms into inert alkanethiol SAMs. Tuning the grafting conditions (surface density of grafting lines and scan rate) allowed us to tailor the molecular density of the DNA platforms ...
Silvia Maria Cristina Rotondi, Paolo Canepa, Elena Angeli, Maurizio Canepa, Ornella Cavalleri   +4 more
doaj   +1 more source

DNA hybridization catalysts and catalyst circuits [PDF]

, 2005
Practically all of life's molecular processes, from chemical synthesis to replication, involve enzymes that carry out their functions through the catalysis of metastable fuels into waste products.
A.J. Turberfield, B. Yurke, B. Yurke, C. Flamm, C. Green, C. Radding, C.D. Mao, C.M. Niemeyer, D.M. Wong, E. Winfree, I.G. Panyutin, I.G. Panyutin, J. Shin, M.N. Stojanovic, M.O. Magnasco, N. Carmi, R.F. Gesteland, S.W. Santoro, W.B. Sherman   +18 more
core   +1 more source

Rapid identification and differentiation of the vaccine strain Rac H from EHV 1 field isolates using a non-radioactive DNA probe [PDF]

, 1992
A method for rapid differentiation between the EHV 1 live vaccine strain Rac H and field isolates is described. Total DNA was isolated from virus-infected small scale cell cultures.
Eichhorn, Werner, Hübert, P. H., Meyer, H., Schwend, C.   +3 more
core   +1 more source

On Critical Relative Distance of DNA Codes for Additive Stem Similarity [PDF]

, 2010
We consider DNA codes based on the nearest-neighbor (stem) similarity model which adequately reflects the "hybridization potential" of two DNA sequences.
D'yachkov, A., Macula, A., Renz, T., Rykov, V., Voronina, A.   +4 more
core   +3 more sources

FRET Imaging of Nonuniformly Distributed DNA SAMs on Gold Reveals the Role Played by the Donor/Acceptor Ratio and the Local Environment in Measuring the Rate of Hybridization

Chemical & Biomedical Imaging, 2023
Mixed DNA SAMs labeled with a fluorophore (either AlexaFluor488 or AlexaFluor647) were prepared on a single crystal gold bead electrode using potential-assisted thiol exchange and studied using Förster resonance energy transfer (FRET).
Adrian Jan Grzędowski, Tianxiao Ma, Dan Bizzotto   +2 more
doaj   +1 more source

Bio-Constrained Codes with Neural Network for Density-Based DNA Data Storage

Mathematics, 2022
DNA has evolved as a cutting-edge medium for digital information storage due to its extremely high density and durable preservation to accommodate the data explosion. However, the strings of DNA are prone to errors during the hybridization process.
Abdur Rasool, Qiang Qu, Yang Wang, Qingshan Jiang   +3 more
doaj   +1 more source