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Double-Stranded DNA Binding Protein Hu
1989The genome of eukaryotes is highly organised, structurally and functionally. The supercoiling of the DNA, its packing around the histone core into nucleosomes, and the ordering of nucleosomes into chromatin results in highly condensed chromosomes in the cell nucleus (Felsenfeld and McGhee, 1986).
K, Wilson +3 more
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DNA Stability and DNA Binding Proteins
1996Publisher Summary This chapter reviews the initial studies that focus on characterizing the factors that contribute to the stability of the genomes of hyperthermophiles, both extrinsic factors, such as the intracellular ionic environment and so-called histone like DNA binding proteins, and intrinsic factors, such as DNA base composition and topology.
R A, Grayling, K, Sandman, J N, Reeve
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The adenovirus DNA-binding protein DBP
Journal of VirologyAdenoviruses are a group of double-stranded DNA viruses that can mainly cause respiratory, gastrointestinal, and eye infections in humans. In addition, adenoviruses are employed as vector vaccines for combatting viral infections, including SARS-CoV-2, and serve as excellent gene therapy vectors.
Luca D. Bertzbach +5 more
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Telomeric DNA binding proteins.
BioEssays : news and reviews in molecular, cellular and developmental biology, 1994The physical ends of eukaryotic chromosomes form a specialized nucleoprotein complex composed of DNA and DNA binding proteins. This nucleoprotein complex, termed the telomere, is essential for chromosome stability. In most organisms, the DNA portion of the nucleo-protein complex consists of simple tandem DNA repeats with one strand guanine rich.
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Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions
Ca-A Cancer Journal for Clinicians, 2021Michael L Cheng +2 more
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The structure, function and evolution of proteins that bind DNA and RNA
Nature Reviews Molecular Cell Biology, 2014William H Hudson, Eric A Ortlund
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A brave new world of RNA-binding proteins
Nature Reviews Molecular Cell Biology, 2018Matthias W Hentze +2 more
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