Results 191 to 200 of about 26,180 (234)

Resolving Sub-Nuclear Architecture from Compartments to Functional Domains. [PDF]

open access: yesInt J Mol Sci
Cavallo M   +4 more
europepmc   +1 more source

A spontaneous termination mechanism of RNA polymerase V shapes the DNA methylation landscape in plants. [PDF]

open access: yesEMBO J
Xie G   +15 more
europepmc   +1 more source

DNA polymerase α-primase can function as a translesion DNA polymerase. [PDF]

open access: yesProc Natl Acad Sci U S A
Mayle R, Georgescu R, O'Donnell ME.
europepmc   +1 more source

The DNA-directed RNA polymerases of soybean

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1973
Abstract Four cellular RNA polymerases have been partially purified from hypocotyls of soybean ( Glycine max ). Enzyme isolation from nuclear preparations indicate the DEAE polymerases I and II are localized within the nucleus. Inhibitor studies showed that DEAE polymerase II was preferentially inhibited by α-amanitin, DEAE peaks III and IV were ...
P A, Horgen, J L, Key
openaire   +3 more sources

Effect of granaticin on the activity of DNA-directed RNA polymerase fromStreptomyces granaticolor

Folia Microbiologica, 1989
DNA-directed RNA polymerase was isolated from wild-type and mutant (asporogenic and granaticin overproducing) Streptomyces granaticolor. The effect of granaticin on the enzyme activity was compared with that of standard transcription inhibitors, rifampicin and rifamycin SV and shown to be zero.
J, Smardová   +3 more
openaire   +2 more sources

Improved prediction of prognosis and therapy response for lung adenocarcinoma after identification of DNA-directed RNA polymerase-associated lncRNAs

Journal of Cancer Research and Clinical Oncology, 2023
DNA-directed RNA polymerase (DDRP) related genes and long non-coding RNAs (lncRNAs) play an important role in the development of lung adenocarcinoma (LUAD), the leading cause of cancer-related death worldwide. Therefore, we aimed to construct a DDRP-associated lncRNA model to predict the prognosis of LUAD and to evaluate its sensitivity to ...
Jiaao, Yu   +3 more
openaire   +2 more sources

On the Binding of Rifampicin to the DNA‐Directed RNA Polymerase from Escherichia coli

European Journal of Biochemistry, 1973
The capacity of RNA polymerase to bind the antibiotic rifampicin is rather sensitive to conditions which lead to conformational changes in the enzyme. Repeated freezing and thawing in 1 M LiCl as well as treatment with guanidinium chloride destroys the binding affinity of the enzyme for the inhibitor. Similarly rifampicin does not associate with any of
U I, Lill, G R, Hartmann
openaire   +2 more sources

The isolation and properties of a DNA-directed RNA polymerase from yeast mitochondria

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1976
A method is described for the rapid isolation of yeast mitochondrial DNA-directed RNA polymerase. The enzyme obtained had a specific activity of 1.56 nmol UMP incorporated per mg protein in 20 min at 37 degrees C, and is some 95% pure. This purified enzyme upon polyacrylamide gel elctrophoresis consists of a single polypeptide of 68 000 mol.
openaire   +2 more sources

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