Results 131 to 140 of about 6,548,876 (337)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Escuela N°116 "Santiago del Estero"

A&P Continuidad, 2020
Ministerio de Obras Públicas DNA.
doaj   +1 more source

Method for the Observation of Macromolecules with the Electron Microscope Illustrated with Micrographs of DNA [PDF]

, 1956
Cecil E. Hall
openalex   +1 more source

Mono- and Trivalent Ions around DNA: A Small-Angle Scattering Study of Competition and Interactions

, 2008
The presence of small numbers of multivalent ions in DNA-containing solutions results in strong attractive forces between DNA strands. Despite the biological importance of this interaction, e.g., DNA condensation, its physical origin remains elusive ...
Andresen, Kurt, Kwok, Lisa W., Lamb, Jessica S., Pabit, Suzette A., Park, Hye Yoon, Pollack, Lois, Qiu, Xiangyun   +6 more
core  

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Estudio y validación de los microsatélites D1S1656, D12S391 y D18S535 en las poblaciones de Antioquia y Chocó

Acta Biológica Colombiana, 2001
En este trabajo se describen las frecuencias alélicas, la distribución fenotípica y los parámetrosestadísticos de interés forense de los loci STRs D1S1656, D12S391 y D18S535, en las pobla-ciones colombianas de Antioquia y Chocó.La tipificación se realizó
JJ. Builes, C. Salazar, M. Martínez-Pancorbo, MA. Moreno, CP. Gómez, ML. Bravo   +5 more
doaj  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

THE EXTENT OF THE ENZYMATIC DEGRADATION OF DESOXYRIBONUCLEIC ACID (DNA) IN PURULENT EXUDATES BY STREPTODORNASE 123 [PDF]

, 1950
Sol Sherry, John P. Goeller
openalex   +1 more source

Mining the virome for insights into type 1 diabetes [PDF]

, 2018
Park, Arnold, Zhao, Guoyan
core   +2 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source