Results 181 to 190 of about 5,185,708 (294)

The DNA-damage response in human biology and disease

Nature, 2009
S. Jackson, J. Bartek
semanticscholar   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

The mirage of DNA methylation in transcriptional regulation of plants. [PDF]

Plant Genome
Civan P, Sammarco I, Banouh M.
europepmc   +1 more source

DNA-DNA hybridization values and their relationship to whole-genome sequence similarities.

International Journal of Systematic and Evolutionary Microbiology, 2007
J. Goris, K. Konstantinidis, J. Klappenbach, T. Coenye, P. Vandamme, J. Tiedje   +5 more
semanticscholar   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

P845: HemaSure-OMXP: A non-toxic venous whole blood collection device enabling the 14-day room temperature stabilization of cell-free DNA

Genetics in Medicine Open
Andrew Wood, Veronika Rapoport, Ying Wang   +2 more
doaj   +1 more source

DNA sequence contamination analyzer (DNASCAN): a supervised analysis toolkit for detecting and removing DNA contaminants. [PDF]

BMC Bioinformatics
Malamon JS.
europepmc   +1 more source

Rapid genetic identification and mapping of enzymatically amplified ribosomal DNA from several Cryptococcus species

Journal of Bacteriology, 1990
R. Vilgalys, M. Hester
semanticscholar   +1 more source

Junk DNA: "DNA zabor" ala "DNA txatar"?

, 2013
Funtzio ezagunik edo argirik ez duen genomaren zatia DNA zabor bezala ezagutzen da. DNA zaborra eratzen duten osagaiak gehiago ikertzen goazen heinean, osagai hauek genometan izan dezaketen garrantzia ere azaleratzen doa. Era berean, hain garrantzia handia egozten ez dioten aurkikuntzak ere egin dira.
openaire   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source