Results 361 to 370 of about 7,795,985 (403)

HMCES corrupts replication fork stability during base excision repair in homologous recombination-deficient cells. [PDF]

open access: yesSci Adv
Peña-Gómez MJ   +9 more
europepmc   +1 more source

Capping DNA with DNA

Biochemistry, 2000
Twelve classes of deoxyribozymes that promote an ATP-dependent "self-capping" reaction were isolated by in vitro selection from a random-sequence pool of DNA. Each deoxyribozyme catalyzes the transfer of the AMP moiety of ATP to its 5'-terminal phosphate group, thereby forming a 5',5'-pyrophosphate linkage.
and Yong Liu   +2 more
openaire   +3 more sources

DNA-DNA interactions

Current Opinion in Structural Biology, 1998
The forces that govern DNA double helix organization are being finally systematically measured. The non-specific longer-range interactions--such as electrostatic interactions, hydration, and fluctuation forces--that treat DNA as a featureless rod are reasonably well recognized.
Helmut H. Strey   +3 more
openaire   +3 more sources

Ligating DNA with DNA

Journal of the American Chemical Society, 2004
Cloning DNA typically involves the joining of target DNAs with vector constructs by enzymatic ligation. A commonly used enzyme for this reaction is bacteriophage T4 DNA ligase, which requires ATP as the energy source to catalyze the otherwise unfavorable formation of a phosphodiester bond.
Alavattam Sreedhara   +2 more
openaire   +2 more sources

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.

Science, 1988
A thermostable DNA polymerase was used in an in vitro DNA amplification procedure, the polymerase chain reaction. The enzyme, isolated from Thermus aquaticus, greatly simplifies the procedure and, by enabling the amplification reaction to be performed at
R. Saiki   +7 more
semanticscholar   +1 more source

DNA Elasticity from Short DNA to Nucleosomal DNA

The Journal of Physical Chemistry B, 2015
Active biological processes like transcription, replication, recombination, DNA repair, and DNA packaging encounter bent DNA. Machineries associated with these processes interact with the DNA at short length (
Garai, Ashok   +3 more
openaire   +4 more sources

DNA topoisomerases and DNA repair

BioEssays, 1988
AbstractDNA topoisomerases are enzymes that can modify, and may regulate, the topological state of DNA through concerted breaking and rejoining of the DNA strands. They have been believed to be directly involved in DNA excision repair, and perhaps to be required for the control of repair as well. The vicissitudes of this hypothesis provide a noteworthy
Robert T. Johnson, C. S. Downes
openaire   +3 more sources

DNA and DNA Extraction

Journal of Natural Resources and Life Sciences Education, 2003
This lesson discusses what DNA is and how it relates to genes and chromosomes. How and why DNA is extracted in the genetic engineering process is also covered. Overview and Objectives - DNA and DNA Extraction This lesson discusses what DNA is and how it relates to genes and chromosomes. How and why DNA is extracted in the genetic engineering process is
Hain, Patricia, Lee, Don
openaire   +2 more sources

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