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Targeting duplex DNA with DNA‐PNA chimeras? Physico‐chemical characterization of a triplex DNA‐PNA/DNA/DNA

Biopolymers, 2004
AbstractTargeting double‐stranded DNA with homopyrimidine PNAs results in strand displacement complexes PNA/DNA/PNA rather than PNA/DNA/DNA triplex structures. Not much is known about the binding properties of DNA‐PNA chimeras. A 16‐mer 5′‐DNA‐3′‐p‐(N)PNA(C) has been investigated for its ability to hybridize a complementary duplex DNA by DSC, CD, and ...
PETRACCONE, LUIGI   +7 more
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DNA Labeling Using DNA Methyltransferases

2016
DNA methyltransferases (MTases) uniquely combine the ability to recognize and covalently modify specific target sequences in DNA using the ubiquitous cofactor S-adenosyl-L-methionine (AdoMet). Although DNA methylation plays important roles in biological signaling, the transferred methyl group is a poor reporter and is highly inert to further ...
Tomkuvienė, Miglė   +2 more
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Eukaryotic DNA polymerases in DNA replication and DNA repair

Chromosoma, 1998
DNA polymerases carry out a large variety of synthetic transactions during DNA replication, DNA recombination and DNA repair. Substrates for DNA polymerases vary from single nucleotide gaps to kilobase size gaps and from relatively simple gapped structures to complex replication forks in which two strands need to be replicated simultaneously ...
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The Detection of Anti-Dna and Dna/Anti-Dna Complexes

Scandinavian Journal of Rheumatology, 1975
(1975). The Detection of Anti-Dna and Dna/Anti-Dna Complexes. Scandinavian Journal of Rheumatology: Vol. 4, No. sup11, pp. 7-11.
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DNA and DNA Evidence*

2010
There are few scientific approaches to human identification that are more effective than a well-trained forensic dentist armed with a set of high-quality dental records and radiographs. Fingerprinting is probably the only other technique used with greater frequency, but as we know, the soft tissue of the extremities does not resist the ravages of ...
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DNA Methyltransferases and DNA Damage

2022
Ever since the discovery of depletion of CG sites in mammalian genomes it has been clear that cytosine DNA methyltransferases (DNMTs) are linked to the rate at which mutations accumulate in DNA. Research in the intervening decades has shown that DNMTs influence mutation rates through the indirect consequences of methylation on the mechanism of mutation
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DNA Looping

Science, 1988
DNA looping is widely used in nature. It is well documented in the regulation of prokaryotic and eukaryotic gene expression, DNA replication, and site-specific DNA recombination. Undoubtedly looping also functions in other protein-DNA transactions such as repair and chromosome segregation.
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[17] DNA-DNA hybridization of single-copy DNA sequences

1993
This chapter is reviews the basic principles of hybridization and the kinetics of reassociation. It provides an overview that summarizes and compares different techniques used in single-copy hybridization. The chapter then examines different estimates of distance derived from melting curves. Native DNA is isolated and purified to remove RNA and protein.
Springer, Mark S., Britten, Roy J.
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