Results 141 to 150 of about 33,588 (237)
Cancer Science, EarlyView.Our work makes the proof of concept that there is a clinical benefit to target both PRMT1 and PRMT5 to maximize the anti‐tumoral effect of chemotherapy in triple negative breast cancer. ABSTRACT Patients with triple‐negative breast cancer (ER−, PR−, and HER2−) are routinely treated with chemotherapies that induce DNA damage.
Charlène Thiebaut +13 more
wiley +1 more source
The FEBS Journal, EarlyView.This study investigates the potential of encapsulin as an antigen display platform for the development of a candidate Salmonella vaccine for poultry. Encapsulin constructs were transiently expressed in Nicotiana benthamiana where they accumulated to high levels.
Carly A. Charron +6 more
wiley +1 more source
The FEBS Journal, EarlyView.Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa +9 more
wiley +1 more source
Effect of Benzo[a]pyrene-DNA Adduct in Cord Blood on the Neurodevelopment of 12-Month-Old Infants in Qingdao City. [PDF]
Neuropsychiatr Dis Treat, 2019 Zhang Y +9 more
europepmc +1 more source
The competitive interplay of 12‐oxophytodienoic acid (OPDA), protein thiols, and glutathione
The FEBS Journal, EarlyView.12‐Oxophytodienoic acid (OPDA) is a phytohormone involved in plant growth and stress defense. Due to its cyclopentenone moiety, OPDA can form Michael adducts with thiol‐containing compounds such as glutathione and cysteine residues of proteins, resulting in alterations of the cellular redox regulatory network.
Madita Knieper +8 more
wiley +1 more source
TANC1::HTRA1 fusion in schwannomas
Brain Pathology, EarlyView.
Ilay Caliskan +3 more
wiley +1 more source
Understanding how enzymes work: the journey to ensemble–function studies
The FEBS Journal, EarlyView.For decades, structure–function has dominated biochemistry. Structures are highly valuable, yet more is needed to achieve a quantitative understanding of biomolecular function, because function emerges from an ensemble of states, rather than a static structure. We describe an ensemble–function framework applied to quantitatively dissect serine protease
Daniel Herschlag, Siyuan Du
wiley +1 more source
Strong impact of sulfotransferases on DNA adduct formation by 4-aminobiphenyl in bladder and liver in mice. [PDF]
Cancer Med, 2018 Li Y +7 more
europepmc +1 more source
Journal of Applied Entomology, EarlyView.ABSTRACT Rachiplusia nu, known as the sunflower looper (SFL) and belonging to the Plusiinae subfamily, is a major defoliator of soybeans, sunflowers and other horticultural crops across southern South America. This species has recently expanded to central and northern regions of Brazil, becoming a key soybean pest.
Leonardo Figueiredo +5 more
wiley +1 more source