Background: Benzo(a)pyrene (B[a]P) is the most widely concerned polycyclic aromatic hydrocarbons (PAHs), which metabolizes benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide (BPDE) in vivo to produce carcinogenic effect on the body.
Ling Guo+16 more
doaj
Retraction: HSP90 Inhibitors Suppress Aryl Hydrocarbon Receptor-Mediated Activation of CYP1A1 and CYP1B1 Transcription and DNA Adduct Formation. [PDF]
Hughes D+4 more
europepmc +1 more source
Designing organometallic compounds for catalysis and therapy [PDF]
Bioorganometallic chemistry is a rapidly developing area of research. In recent years organometallic compounds have provided a rich platform for the design of effective catalysts, e.g. for olefin metathesis and transfer hydrogenation.
Abraha Habtemariam+188 more
core +1 more source
Multi-DNA Adduct and Abasic Site Quantitation In Vivo by Nano-Liquid Chromatography/High-Resolution Orbitrap Tandem Mass Spectrometry: Methodology for Biomonitoring Colorectal DNA Damage. [PDF]
Konorev D, Yao L, Turesky RJ.
europepmc +1 more source
Notizen: Contribution of Monofunctional Adducts formed by Furocoum arins with DNA to the Inhibition of Nucleic Acids Synthesis [PDF]
F. Baccichetti+4 more
openalex +1 more source
Use of DNA adduct and histopathological defects as indications for bio-persistence potency of zinc oxide nanoparticles in gastropod, Monacha cartusiana (Mǜller) after short-term exposure. [PDF]
Abdel-Halim KY+4 more
europepmc +1 more source
Error-free excision of the cytotoxic,mutagenic N2-deoxyguanosine DNA adduct formed in human fibroblasts by (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. [PDF]
Li Yang, Vincent Maher, J J McCormick
openalex +1 more source
Processing and Bypass of a Site-Specific DNA Adduct of the Cytotoxic Platinum-Acridinylthiourea Conjugate by Polymerases Involved in DNA Repair: Biochemical and Thermodynamic Aspects. [PDF]
Hreusova M, Brabec V, Novakova O.
europepmc +1 more source
Genotoxic Pyrrolizidine Alkaloids — Mechanisms Leading to DNA Adduct Formation and Tumorigenicity
Plants that contain pyrrolizidine alkaloids are widely distributed in the world. Although pyrrolizidine alkaloids have been shown to be genotoxic and tumorigenic in experimental animals, the mechanisms of actions have not been fully understood.
P. Fu, Q. Xia, G. Lin, M. Chou
semanticscholar +1 more source
Co-Exposure to Aristolochic Acids I and II Increases DNA Adduct Formation Responsible for Aristolochic Acid I-Mediated Carcinogenicity in Rats. [PDF]
Bárta F+8 more
europepmc +1 more source