Results 161 to 170 of about 40,057 (283)

Defining in vivo dose-response curves for kidney DNA adduct formation of aristolochic acid I in rat, mouse and human by an in vitro and physiologically based kinetic modeling approach. [PDF]

J Appl Toxicol, 2020
Abdullah R, Wesseling S, Spenkelink B, Louisse J, Punt A, Rietjens IMCM.   +5 more
europepmc   +1 more source

Comparison of Three Sympatric Desert Lizards: Digestive Tract Structure, Digestive Enzyme Activities, Gut Microbiota, and Metabolites

Integrative Zoology, EarlyView.
We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley   +1 more source

Tissue Organoid Cultures Metabolize Dietary Carcinogens Proficiently and Are Effective Models for DNA Adduct Formation. [PDF]

Chem Res Toxicol
Caipa Garcia AL, Kucab JE, Al-Serori H, Beck RSS, Bellamri M, Turesky RJ, Groopman JD, Francies HE, Garnett MJ, Huch M, Drost J, Zilbauer M, Arlt VM, Phillips DH.   +13 more
europepmc   +1 more source

Mainstream and Sidestream Cigarette Smoke-Induced DNA Adducts in C7Bl and DBA Mice

, 1993
C. Gary Gairola, Han‐Ping Wu, Ramesh C. Gupta, John N. Diana   +3 more
openalex   +1 more source

Formation of DNA Adducts by Ellipticine and Its Micellar Form in Rats — A Comparative Study [PDF]

, 2014
Marie Stiborová, Zuzana Manhartova, Petr Hodek, Vojtěch Adam, René Kizek, Eva Frei   +5 more
openalex   +1 more source

Exposures in Indoor Air Affecting Health

Allergy, EarlyView.
ABSTRACT Indoor air quality (IAQ) is influenced by a wide range of chemical, biological and physical agents that can negatively impact physical, immunological and mental health. Adverse health effects depend on the type and concentration of pollutants, duration of exposure, and individual susceptibility.
Maria Hartiala, Varpu Elenius, Alicia Aguado Pesquera, Silas Androulakis, Isabella Annesi‐Maesano, Artur Badyda, Sicco Brandsma, Ioanna Chatziprodromidou, Goran Gajski, Judith Garcia‐Aymerich, Chiara Giorio, Timo Hugg, Jouni J. K. Jaakkola, Sarah Koch, Pim E. G. Leonards, Angeliki Matrali, Lisa Melymuk, Natalie Mueller, Adam Muszyński, Jet Opbroek, Inês Paciência, Spyros N. Pandis, Sofya Pozdniakova, Aino K. Rantala, Sandra Rodríguez Sufuentes, Linda Schenk, Eva Sugeng, Adrià Sunyer‐Caldú, Apostolos Vantarakis, Alexander Zherebker, Ernesto Alfaro‐Moreno, Pernilla Bohlin Nizzetto, José Fermoso Dominguez, Stylianos Karatzas, Francesco Mureddu, Heidi Salonen, Nikolaos Papadopoulos, Tuomas Jartti, the IDEAL Consortium   +38 more
wiley   +1 more source

Chemical Modification of DNA with Muta-Carcinogens. I. 3-Amino-1-methyl-5H-pyrido[4,3-b]indole and 2-Amino-6-methyldipyrido[1,2-a:3 prime ,2 prime -d]imidazole: Metabolic Activation and Structure of the DNA Adducts

, 1985
Yuichi Hashimoto, Koichi Shudo
openalex   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Naphthalene DNA Adduct Formation and Tolerance in the Lung. [PDF]

Nucl Instrum Methods Phys Res B, 2019
Buchholz BA, Carratt SA, Kuhn EA, Collette NM, Ding X, Van Winkle LS.   +5 more
europepmc   +1 more source

Dietary phytate lowers K-ras mutational frequency, decreases DNA-adduct and hydroxyl radical formation in azoxymethane-induced colon cancer. [PDF]

Iran J Basic Med Sci, 2020
Pallem PVSP, Bodiga S, Bodiga VL.
europepmc   +1 more source