Results 181 to 190 of about 40,057 (283)

The competitive interplay of 12‐oxophytodienoic acid (OPDA), protein thiols, and glutathione

open access: yesThe FEBS Journal, EarlyView.
12‐Oxophytodienoic acid (OPDA) is a phytohormone involved in plant growth and stress defense. Due to its cyclopentenone moiety, OPDA can form Michael adducts with thiol‐containing compounds such as glutathione and cysteine residues of proteins, resulting in alterations of the cellular redox regulatory network.
Madita Knieper   +8 more
wiley   +1 more source

Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause

open access: yesImmunology, EarlyView.
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley   +1 more source

Enhanced DNA adduct formation by benzo[a]pyrene in human liver cells lacking cytochrome P450 oxidoreductase.

open access: yesMutat Res Genet Toxicol Environ Mutagen, 2020
Reed L   +3 more
europepmc   +1 more source

A new species of Peckoltia (Siluriformes, Loricariidae) from the rapids of the Rio Tocantins‐Araguaia basin, Brazil

open access: yesJournal of Fish Biology, EarlyView.
Abstract Here, we describe a new species of Peckoltia (Loricariidae; Hypostominae) from the rapids of the Rio Tocantins‐Araguaia basin, previously identified as Peckoltia vittata, using an integrative taxonomy approach. The new species is distinguished from congeners by ventral region presenting diffuse stripes on surface, not presenting spots or ...
Felipe Arian Andrade de Araújo   +3 more
wiley   +1 more source

Correlation of Platinum Cytotoxicity to Drug-DNA Adduct Levels in a Breast Cancer Cell Line Panel. [PDF]

open access: yesChem Res Toxicol, 2018
Wang S   +7 more
europepmc   +1 more source

Acrylamide induces specific DNA adduct formation and gene mutations in a carcinogenic target site, the mouse lung [PDF]

open access: bronze, 2014
Yuji Ishii   +8 more
openalex   +1 more source

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