Results 211 to 220 of about 40,057 (283)

Pathogen‐reduced plasma, cryoprecipitate reduced for therapeutic plasma exchange

Transfusion, EarlyView.
Abstract Background Therapeutic plasma exchange (TPE) for thrombotic thrombocytopenic purpura (TTP) and auto‐immune disorders involves repeated patient exposure to allogenic plasma with the risk of transfusion‐transmitted infection (TTI).
Florian Tupin, Clarisse Mouriaux, Beatrice Hechler, Kaja Kaastrup, Subra Yegneswaran, Laurence Corash, Pierre H. Mangin   +6 more
wiley   +1 more source

An endogenous DNA adduct as a prognostic biomarker for hepatocarcinogenesis and its prevention by Theaphenon E in mice. [PDF]

Hepatology, 2018
Fu Y, Silverstein S, McCutcheon JN, Dyba M, Nath RG, Aggarwal M, Coia H, Bai A, Pan J, Jiang J, Kallakury B, Wang H, Zhang YW, Giaccone G, He AR, Chung FL.   +15 more
europepmc   +1 more source

Clinical validation of a DNA methylation biomarker associated with overall survival of relapsed ovarian cancer patients

International Journal of Cancer, Volume 158, Issue 7, Page 1821-1835, 1 April 2026.
What's new? Most patients with ovarian cancer (OC) relapse after first‐line chemotherapy, and prognosis with second‐line treatment depends largely on the platinum‐free interval. However, reliable biomarkers to predict response to second‐line therapy remain lacking.
Muhammad Habiburrahman, Nahal Masrour, Naina Patel, Anna M. Piskorz, Robert Brown, James D. Brenton, Iain A. McNeish, James M. Flanagan   +7 more
wiley   +1 more source

Ultrasensitive High-Resolution Mass Spectrometric Analysis of a DNA Adduct of the Carcinogen Benzo[a]pyrene in Human Lung. [PDF]

Anal Chem, 2017
Villalta PW, Hochalter JB, Hecht SS.
europepmc   +1 more source

DNA Topology on an Increase in Positive Writhing Number of DNA: Conformation Changes in the Time Course of cis-Diamminedichloroplatinum(II)-DNA Adducts.

, 2001
Shigeki Kobayashi, Yoshihide Nakamura, Tamae MAEHARA, Hajime Hamashima, Masanori Sasatsu, Koji Asano, Yukihiko Ohishi, Akira Tanaka   +7 more
openalex   +2 more sources

Variant Update on ASCC1 : Characterization of the First Homozygous Missense Variant Involved in Prenatal‐Onset Spinal Muscular Atrophy With Congenital Bone Fractures 2

American Journal of Medical Genetics Part A, Volume 200, Issue 3, Page 744-748, March 2026.
ABSTRACT Spinal muscular atrophy with congenital bone fractures 2 is a rare and severe autosomal recessive neuromuscular disorder caused by pathogenic variants in ASCC1. This condition characterized by prenatal onset of severe hypotonia with fetal hypokinesia and congenital contractures results in arthrogryposis multiplex congenita, and increased ...
A. Civit, L. Kerbellec, D. Laurenceau, D. C. Ung, M. P. Moizard, N. Ronce, P. Gueguen, F. Laumonnier, A. C. Bréhin, F. Marguet, A. Laquerrière, A. M. Bergemer Fouquet, J. Cirier, S. Blesson, S. Arpin, M. Jeanne, M. L. Vuillaume   +16 more
wiley   +1 more source

Genetic control of predominantly error-free replication through an acrolein-derived minor-groove DNA adduct. [PDF]

J Biol Chem, 2018
Yoon JH, Hodge RP, Hackfeld LC, Park J, Roy Choudhury J, Prakash S, Prakash L.   +6 more
europepmc   +1 more source

Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides

Journal of Peptide Science, Volume 32, Issue 3, March 2026.
As an alternative to the conventional approach, which combines amino acid monomers in a one‐by‐one fashion to peptide derivatives, the chemical modification of existing peptides has attracted significant attention in recent years. However, such approaches generally target the reactive functional groups in cysteine and lysine residues, particularly in ...
Yoshitaka Moriyama, Hikari Sada, Takeshi Nanjo   +2 more
wiley   +1 more source

Activation of dihaloalkanes by glutathione conjugation and formation of DNA adducts.

, 1987
F. Peter Guengerich, Lisa A. Peterson, Joan L. Cmarik, Naofumi Koga, Philip B. Inskeep   +4 more
openalex   +2 more sources

Covalent Peptide‐Based N‐Myc/Aurora‐A Inhibitors Bearing Sulfonyl Fluoride Warheads

Journal of Peptide Science, Volume 32, Issue 3, March 2026.
N‐Myc‐derived peptidomimetics bearing aryl sulfonyl fluoride warheads were shown to act as effective N‐Myc/Aurora‐A PPI inhibitors, selectively labelling Aurora‐A in a recognition‐directed manner. ABSTRACT Orthosteric inhibition of the N‐Myc/Aurora‐A protein–protein interaction (PPI) represents a potential mechanism by which degradation of N‐Myc can be
Robert S. Dawber, Diana Gimenez, George W. Preston, Megan H. Wright, Richard Bayliss, Stuart L. Warriner, Andrew J. Wilson   +6 more
wiley   +1 more source