Results 161 to 170 of about 55,387 (283)

Biochemical Battle: Influence of Omega-6 Fatty Acids on the Formation of DNA Adducts with 4-HNE. [PDF]

Curr Issues Mol Biol
Błaszczyk E, Karwowski BT.
europepmc   +1 more source

Snapshots of Motion: A Novel Structural Intermediate Reveals Conserved Dynamics in Archaeal DNA Ligases

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We present the first x‐ray crystallographic structural evidence of an archaeal DNA ligase showing the AMP covalent adduct together with further cofactor hydrolysis, capturing a transient intermediary in the first step of the ligation reaction, triggered by the pyrophosphate hydrolysis.
A. X. Quintana‐Armas, E. Flores‐Hernández, C. Cardona‐Félix, E. Rudiño‐Piñera   +3 more
wiley   +1 more source

A simplified LC-MS-based method for sensitive analysis of DNA adducts utilizing accessible in vitro metabolism models. [PDF]

Arch Toxicol
Gerdemann A, Behrens M, Günther G, Ghallab A, Hengstler JG, Humpf HU, Esselen M.   +6 more
europepmc   +1 more source

Feeding Brassica vegetables to rats leads to the formation of characteristic DNA adducts (from 1-methoxy-3-indolylmethyl glucosinolate) in many tissues. [PDF]

Arch Toxicol, 2022
Glatt H, Engst W, Florian S, Schreiner M, Baasanjav-Gerber C.   +4 more
europepmc   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

DNA adducts form in mouse lung and liver after oral naphthalene exposure. [PDF]

Toxicol Sci
Domanico MC, Collette NM, Ubick E, Ding X, Buchholz BA, Van Winkle LS.   +5 more
europepmc   +1 more source

Correction: Effects of Benzo [a]pyrene-DNA adducts, dietary vitamins, folate, and carotene intakes on preterm birth: a nested case-control study from the birth cohort in China. [PDF]

Environ Health, 2022
Zhao N, Wu W, Cui S, Li H, Feng Y, Guo L, Zhang Y, Wang S.   +7 more
europepmc   +1 more source

Effects of DNA Adduct Structure and Sequence Context on Strand Opening of Repair Intermediates and Incision by UvrABC Nuclease

, 2003
Yue Zou, Steven M. Shell, Christopher D. Utzat, Charlie Luo, Zhengguan Yang, Nicholas E. Geacintov, Ashis K. Basu   +6 more
openalex   +1 more source

Atomic‐Precision Symmetry Breaking in Bi‐O‐Ti Sites Enables ROS Generation for Bactericidal and Osteosarcoma Therapy

Rare Metals, EarlyView.
ABSTRACT Photocatalytic therapy, which generates reactive oxygen species (ROS) upon light irradiation, has garnered significant interest for antibacterial and anticancer applications. This study establishes a doping‐engineered photocatalytic platform for antibacterial activity and precision osteosarcoma therapy by atomically constructing asymmetric Bi ...
Jun Gu, Haitao Yuan, Bo Chu, Tianqi Wang, Jin Fan, Xuan Sun, Feng Shi, Qinqin Liu, Xiaojun Feng   +8 more
wiley   +1 more source

Effect of methyl DNA adducts on 3'-5' exonuclease activity of human TREX1. [PDF]

Biochem J
Tuti N, Shaji UP, Das S, Anindya R.
europepmc   +1 more source