Results 161 to 170 of about 2,409,493 (295)

Correction: Effects of Benzo [a]pyrene-DNA adducts, dietary vitamins, folate, and carotene intakes on preterm birth: a nested case-control study from the birth cohort in China. [PDF]

Environ Health, 2022
Zhao N, Wu W, Cui S, Li H, Feng Y, Guo L, Zhang Y, Wang S.   +7 more
europepmc   +1 more source

FB23‐2 and Cisplatin Synergize to Inhibit Head and Neck Squamous Cell Carcinoma by Targeting the XPF/ERCC1 Complex

Cancer Science, EarlyView.
FB23‐2 potentiates cisplatin's antitumor efficacy in head and neck squamous cell carcinoma by disrupting XPF/ERCC1 complex assembly and nuclear translocation, thereby suppressing DNA damage repair machinery and amplifying platinum‐induced tumor cell death.
Yaoqi Jiang, Hongshi Cai, Yue Zhu, Jianfeng Liang, Hongyu Li, Fan Song, Ziyi Wang, Jinsong Hou   +7 more
wiley   +1 more source

Biomonitoring of aristolactam-DNA adducts in human tissues using ultra-performance liquid chromatography/ion-trap mass spectrometry.

Chemical Research in Toxicology, 2012
B. Yun, T. Rosenquist, Viktoriya S. Sidorenko, C. Iden, Chung-Hsin Chen, Y. Pu, R. Bonala, F. Johnson, K. Dickman, A. Grollman, R. Turesky   +10 more
semanticscholar   +1 more source

Targeting PRMTs Creates Vulnerability of DNA Double‐Stand Break Repair Pathways, and Potentiates Chemotherapy Efficacy in TNBC

Cancer Science, EarlyView.
Our work makes the proof of concept that there is a clinical benefit to target both PRMT1 and PRMT5 to maximize the anti‐tumoral effect of chemotherapy in triple negative breast cancer. ABSTRACT Patients with triple‐negative breast cancer (ER−, PR−, and HER2−) are routinely treated with chemotherapies that induce DNA damage.
Charlène Thiebaut, Sébastien Martinez, Ludivine Pruvost, Louisane Eve, Rania El‐Botty, Laura Sourd, Elodie Montaudon, Ahmed Dahmani, Heloise Derrien, Stéphanie Sentis, Coralie Poulard, Elisabetta Marangoni, Olivier Trédan, Muriel Le Romancer   +13 more
wiley   +1 more source

Polycyclic Aromatic Hydrocarbon-DNA Adducts in Gulf of Mexico Sperm Whale Skin Biopsies Collected in 2012. [PDF]

Toxicol Sci, 2021
Poirier MC, Marsili L, Fossi MC, Godard-Codding CAJ, Hernandez-Ramon EE, Si N, Divi KV, Divi RL, Kerr I, Wise JP, Wise CF, Wise SS, Aboueissa AE, Wise JTF, Wise JP.   +14 more
europepmc   +1 more source

Quantitation of DNA adducts by stable isotope dilution mass spectrometry.

Chemical Research in Toxicology, 2012
N. Tretyakova, Melissa M. Goggin, Dewakar Sangaraju, G. Janis   +3 more
semanticscholar   +1 more source

Plant‐produced encapsulin displays non‐typhoidal Salmonella enterica antigens and assembles into mosaic nanoparticles

The FEBS Journal, EarlyView.
This study investigates the potential of encapsulin as an antigen display platform for the development of a candidate Salmonella vaccine for poultry. Encapsulin constructs were transiently expressed in Nicotiana benthamiana where they accumulated to high levels.
Carly A. Charron, Angelo Kaldis, Shabnam Shamriz, Justin B. Renaud, Moussa S. Diarra, Christopher P. Garnham, Rima Menassa   +6 more
wiley   +1 more source

Rapid, direct detection of bacterial topoisomerase 1-DNA adducts by RADAR/ELISA. [PDF]

Anal Biochem, 2020
Sinha D, Kiianitsa K, Sherman DR, Maizels N.   +3 more
europepmc   +1 more source

Use of LC-MS/MS and stable isotopes to differentiate hydroxymethyl and methyl DNA adducts from formaldehyde and nitrosodimethylamine.

Chemical Research in Toxicology, 2012
Kun Lu, Sessaly Craft, Jun Nakamura, B. Moeller, J. Swenberg   +4 more
semanticscholar   +1 more source

Deciphering the properties and reaction mechanism of anhydromevalonate phosphate decarboxylase, a prenylated flavin mononucleotide‐dependent enzyme in the archaeal mevalonate pathway

The FEBS Journal, EarlyView.
Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa, Natsumi Matsushima, Soma Ishimine, Honoka Nakamoto, Hajime Hayakawa, Yoko Yasuno, Tetsuro Shinada, Hiroshi Kawaide, Tomokazu Ito, Hisashi Hemmi   +9 more
wiley   +1 more source