Naphthalene genotoxicity: DNA adducts in primate and mouse airway explants. [PDF]
Toxicol Lett, 2019 Carratt SA +6 more
europepmc +1 more source
Diverse reactivity of maleimides in polymer science and beyond
Polymer International, Volume 74, Issue 4, Page 296-306, April 2025.This mini‐review provides a thorough overview of maleimide chemistry, highlighting its diverse reactivity in polymer and materials science applications. Abstract Maleimides are remarkably versatile functional groups, capable of participating in homo‐ and copolymerizations, Diels–Alder and (photo)cycloadditions, Michael additions, and other reactions ...
Bruce E Kirkpatrick +2 more
wiley +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The homo‐dimeric, ring‐shaped bacterial DNA sliding clamp, β‐clamp, is a central hub in DNA replication and repair. It interacts with a plethora of proteins via their short linear motifs, binding to the same hydrophobic binding pocket on β‐clamp. Although the structure, functions, and interactions of β‐clamp have been amply studied, less focus
Signe Simonsen +5 more
wiley +1 more source
Dietary Carcinogens and DNA Adducts in Prostate Cancer. [PDF]
Adv Exp Med Biol, 2019 Bellamri M, Turesky RJ.
europepmc +1 more source
Proteolytic stabilization of a spider venom peptide results in an orally active bioinsecticide
Pest Management Science, EarlyView.Selective editing out of an insect gut protease cleavage site renders a spider‐derived insecticidal peptide active by ingestion by insect pests. Abstract BACKGROUND The toxin peptide U1‐AGTX‐Ta1b from the Hobo spider, Eratigena agrestis (Walckenaer, 1802), was studied to determine its potential to serve as a bioinsecticide.
Breck R. Davis +12 more
wiley +1 more source
Micro‐ and nanomotors in biomedical applications
Responsive Materials, EarlyView.Micro‐ and nanomotors (MNMs), as autonomous devices converting chemical or external energy into mechanical propulsion, have emerged as transformative drug delivery platforms in biomedicine. This review systematically outlines the design principles governing MNMs' propulsion and operation, highlights the applications of MNMs in disease treatment, and ...
Xiangyu Meng, Yuqi Tang, Quan Li
wiley +1 more source
Infection with carcinogenic helminth parasites and its production of metabolites induces the formation of DNA-adducts. [PDF]
Infect Agent Cancer, 2019 Gouveia MJ +5 more
europepmc +1 more source
Secretome Profiling in Axon Regeneration: Emerging Techniques and Therapeutic Translation
Sensory Neuroscience, EarlyView.ABSTRACT The secretome refers to the in vivo ensemble of molecular entities that are found in interstitial spaces. It is then the mere secreted products of the cells, as all biomolecules in the interstitial cellular spaces also undergo modifications. The fractionated secretome may hold potential as a cell‐free therapy option due to its role in tissue ...
Maria D. Cabrera +3 more
wiley +1 more source
Targeting Tyrosyl-DNA phosphodiesterase I to enhance toxicity of phosphodiester linked DNA-adducts. [PDF]
Cancer Drug Resist, 2019 Brettrager EJ, van Waardenburg RCAM.
europepmc +1 more source
Plasma Functionalization Enables Diffusion Control of Reactive Oxygen Species
Small, EarlyView.Plasma surface functionalization of thin films enables controlled delivery of reactive oxygen species (ROS) generated by catalytic coatings. This approach ensures efficacy driven by radical activity rather than direct redox reactions or leaching. The selective release of radicals with distinct lifetimes is linked to both antimicrobial and antiviral ...
Paula Navascués +11 more
wiley +1 more source