Results 231 to 240 of about 53,252 (284)
Amplification of Photochemical Chiroptical Activity of Chiral Gold Nanocubes
Small, EarlyView.“Chiral gold nanocubes (AuNCs) enable polarization‐dependent plasmonic catalysis with exceptional photochemical circular dichroism. Circularly polarized light drives hot‐electron‐induced reactions with asymmetric reaction rates, monitored via operando SERS, with photochemical g‐factors exceeding optical limits.
Shashank K. Gahlaut +8 more
wiley +1 more source
A recyclable type‐I photosensitizer to enable red‐light‐driven gram‐scale aerobic photocatalysis
Smart Molecules, EarlyView.We report a recyclable type‐I photosensitizer, EtNBS‐H, which enables efficient red‐light‐driven photooxidation with conversion exceeding 99%. Its strong absorption of red light enhances its scalability for industrial applications. EtNBS‐H can be easily recovered and reused through a simple pH‐tunable acid‐base reaction, achieving a recovery rate of ...
Shirong Yan +4 more
wiley +1 more source
Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components
Small Methods, EarlyView.The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu +6 more
wiley +1 more source
Small Methods, EarlyView.Native mass spectrometry enables the label‐free study of noncovalent protein‐ligand complexes; however, it is incompatible with conventional molecular biology buffers. By exploiting the dependence of flow dynamics on the hydrodynamic radius, proteins are seperated, including protein‐ligand complexes, from non‐volatile salts and unbound small molecules ...
Jonathan Eisert +10 more
wiley +1 more source
Shining Bright at 960 nm: A 28‐Silver‐Atom Nanorod Stabilized by DNA
Small Structures, EarlyView.Single‐crystal X‐ray data reveal the structure of a 28‐silver‐atom cluster wrapped within two DNA oligomers. In the crystalline state, two chlorido ligands are detected, which are absent in the mass spectrometry data of the solution state. With 12 valence electrons, the silver cluster has an absorption band situated at 835 nm and an emission peaking at
Giacomo Romolini +8 more
wiley +1 more source
Small Structures, EarlyView.The self‐therapeutic nanocarriers PCOH nanoparticles (NPs) are self‐assembled from the caffeic acid‐derived polyphenolic polymer Ph‐CaA‐OH by nanoprecipitation, and can exhibit dose‐dependent cytotoxicity against triple‐negative breast cancer by promoting reactive oxygen species generation, inducing DNA damage, and suppressing epithelial‐mesenchymal ...
Lezong Chen +6 more
wiley +1 more source
Ionogel‐Dominated Wearable Sensors for Reliable Health Monitoring
SusMat, EarlyView.Ionogels have emerged as promising materials for health monitoring due to their flexibility, thermal stability, and ionic conductivity, yet challenges remain in ensuring reliable performance. This review mainly focuses on the structure‐performance relationships of ionogels towards long‐term health monitoring, including precise designs of robust ...
Wenzhe Xiao +7 more
wiley +1 more source
Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?
Acta Ophthalmologica, EarlyView.Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs +12 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.▪ Background and Purpose NLRP3 is up‐regulated in inflammatory and autoimmune diseases. The development of NLRP3 inhibitors is challenged by the identification of compounds with distinct mechanisms of action avoiding side effects and toxicity. Triptolide is a natural product with multiple anti‐inflammatory activities, but a narrow therapeutic window ...
Mo‐Yu Ding +5 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and purpose Thiopurines are used in paediatric inflammatory bowel disease (IBD), but some patients do not respond. Because the gut microbiota influences drug efficacy and IBD‐patient microbiota presents increased bacterial abundance, we investigated the impact of candidate Enterobacteriaceae on drug cytotoxicity, metabolism and ...
Martina Franzin +13 more
wiley +1 more source