Results 221 to 230 of about 1,695,496 (296)

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

DNA-based identification uncovers the illegal trade of sea cucumbers from Brazil. [PDF]

Sci Rep
Fantinelli AC, Dos Santos N, Junior CER, de Carvalho DEV, da Costa RC, Porto-Foresti F, Utsunomia R.   +6 more
europepmc   +1 more source

Engineered molecular diagnostic strategies for hepatocellular carcinoma: Integrating flexible photonic barcodes, liquid biopsies, and AI‐enhanced sensing platforms

FlexMat, EarlyView.
Abstract Early diagnosis of hepatocellular carcinoma (HCC) remains challenging because conventional serum biomarkers, especially alpha‐fetoprotein (AFP), show limited sensitivity for early‐stage disease. Recent progress in engineered molecular diagnostics provides new opportunities to improve HCC detection through integrated material, molecular, and ...
Jingzhi Xue, Wanqi Yang, Xiaoyu Liu, Xuehui Chu, Wei Li, Jinglin Wang   +5 more
wiley   +1 more source

DNA Barcoding Reveals Hidden Genetic Diversity and Environmental Correlates of Lineage Differentiation in <i>Neozavrelia</i> Goetghebuer & Thienemann, 1941 (Diptera: Chironomidae). [PDF]

Insects
Xie TY, Zhang Y, Chen YZ, Liu Z, Lin XL.
europepmc   +1 more source

Internet of Things and blockchain applications in food audit, authenticity, and traceability: A systematic review

Food Biomacromolecules, EarlyView.
Abstract This review evaluates the integrated applications of the Internet of Things (IoT) and blockchain technologies in enhancing food audit systems, authenticity verification, and supply chain traceability, transparency, and data reliability. Following Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines, a systematic review
S. Sriranjani, Samuel Ayofemi Olalekan Adeyeye   +1 more
wiley   +1 more source

Toward scalable species descriptions for dark taxa: the role of molecular data. [PDF]

Zookeys
Sharkey MJ, Mutanen M, Baker A, Brown BV, Butcher BA, Dowling APG, Godfray HCJ, Hallwachs W, Hausmann A, Hebert PDN, Inclán DJ, Janzen DH, Kiljunen N, Miller SE, Oliveira G, Packer L, Quicke DLJ, Skevington JH, Steinke D, Hernández Ugalde JA, Vogler AP, Hartop E.   +21 more
europepmc   +1 more source

Delimiting Andean catfish species of the families Astroblepidae and Loricariidae (Ostariophysi, Siluriformes) in the Peruvian Andes using DNA barcodes. [PDF]

Zookeys
De la Sota A, Hidalgo M, Estivals G, Faustino-Fuster D, Meza-Vargas V, Caminade P, Bêche L, Britzke R R, Steinke D, Hubert N.   +9 more
europepmc   +1 more source

Recent Advances in Luminescent Hydrogen‐Bonded Organic Frameworks (HOFs): Linker Design, Phosphorescence, and Smart Responsiveness

Information &Functional Materials, EarlyView.
Luminescent Hydrogen‐bonded organic frameworks (HOFs) provide an innovative platform for sensing and optoelectronic applications. This review outlines design principles, recent advances in synthesis and optical tuning, diverse sensing applications, and discusses current challenges and future directions for HOFs.
Heng Wu, Fengqi Wang, Zhuoyan Dong, Yuanchao Lv, Zhangjing Zhang   +4 more
wiley   +1 more source

Integrative identification of insect flower visitors associated with avocado flowering in Western Australia. [PDF]

Environ Entomol
Taniguchi M, Hardy G, Xu W.
europepmc   +1 more source

Impact of Single‐Cell RNA Reference Selection for the Deconvolution of Breast Cancer Spatial Transcriptomics Datasets

International Journal of Cancer, EarlyView.
ABSTRACT Spot‐based spatial transcriptomics (ST) allows for unbiased gene expression analysis within tissue architecture, overcoming the limitations of single‐cell RNA sequencing (scRNA‐seq) by preserving spatial context. However, the high spatial resolution in ST leads to cellular heterogeneity within spots, requiring computational deconvolution to ...
Stefan Altendorfer, Scott J. Walker, Carsten O. Daub   +2 more
wiley   +1 more source